Application Note: Chiral LC-MS Analysis of the Fungicide Tebuconazole
21 March 2019

This application note presentes an effective LC-MS method for the separation of Tebuconazole,  a fungicide used as wood preservative. A reversed phase separation mode was required and mobile phase had to contain acid for ionisation. The YMC CHIRAL ART cellulose-SC was determined to be the most suitable column for further method development. Tebuconazole was detected in the electrospray positive ionisation mode under optimised ion source and fragment ion transmission settings.