Application Note: PVA microcarriers for Vero cell expansion
19 April 2024

Microcarrier cultures have a strong history in large-scale production of anchorage-dependent mammalian cells, notably in the vaccine industry. Kuraray addresses the growing demand for increased cell yields by introducing PVA microcarriers, a novel hydrogel-based microcarrier specifically designed for cell cultivation. PVA hydrogel, known for its biocompatibility, provides an optimal microenvironment for cell growth. These microcarriers enhance surface area-to-volume ratio, fostering cell growth. The report focuses on expanding Vero cells on Kuraray's PVA microcarriers. Vero cells, crucial for producing viral vaccines, are well-suited for microcarrier-based cultivation due to their anchorage-dependent nature and high quantities required for vaccine manufacturing.