ResourceSeparations

LC-MS of intact therapeutic monoclonal antibodies using Agilent AdvanceBio RP-mAb

15 Jul 2021

In this application note, Agilent Technologies analyze multiple therapeutic monoclonal antibodies (mAbs), including an antibody drug conjugate (ADC), using AdvanceBio RP-mAb columns in an LC-MS method. This approach delivered fast analysis times and accurate mass determination of intact mAbs.

Agilent 1290 Infinity II LC System

Agilent Technologies

The 1290 Infinity II LC System is an ultra-high performance LC that has market-leading sample capacity and is designed for the lowest dispersion for the most challenging ultra-HPLC experiments. The 1290 Infinity II LC system is designed to be both a HPLC and high-end UHPLC system in a single flow path, giving you robust and excellent performance no matter what application you are running while seamlessly integrating into your existing laboratory environment.

(91)

Links

Tags

LC-MS of intact therapeutic monoclonal antibodies using Agilent AdvanceBio RP-mAb