SMARCA4 / BRG1 rat antibody (mAb) (Clone 3G4)
BRG1 (Brahma-related gene-1, SNF2b) is the central catalytic ATPase subunit of numerous chromatin-remodeling complexes, including SWI/SNF. These complexes are able to use energy from ATP hydrolysis to physically disrupt chromatin architecture of target promoters and facilitate the binding of transcription factors to nucleosomal DNA. BRG1 is a co-regulator of transcription and has been implicated in the activation and repression of gene expression through the modulation of chromatin in various tissues and physiological conditions. This protein plays a major role in many cellular processes such as DNA replication, repair and recombination. Mammalian BRG1 is usually associated with approximately 10-12 BAF subunits or other proteins involved in regulation of gene expression.
Product Details
- Cat. No.
- 39807
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rat
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Reviews
Good quality
Western Blot
Ok for whole cell lysate, not sure if sensitivity is good enough for IP/co-IP samples.
Review Date: 16 Sept 2016 | Active Motif
Applications
- Immunofluorescence (IF)
- Western Blotting (WB)
Antibody Overview
About the company
Active Motif
Active Motif is the industry leader in developing and delivering innovative tools to enable epigenetics and gene regulation research. We are committed to providing the highest quality products and superior service & support to serve the life science, clinical and pharmaceutical/drug discovery communities. Whether you are an expert in the field of epigenetics or a researcher interested in integrating epigenetics research into your studies, Active Motif offers a comprehensive portfolio of epigenetics-related products and services and the support of our team of epigenetic experts to provide complete and innovative solutions to tackle your scientific inquiries.