SETD2 Rabbit pAb
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.
Product Details
- Cat. No.
- A3194
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - SETD2 antibody (A3194)
The supplier does not provide quotations for this antibody through SelectScience. You can search for similar antibodies in our Antibody Directory.
Reviews
Good antibodies for detection of SETD2 by western blot!
Western blot
I used these antibodies with cell lysates extracted from lung cancer cell lines (A549 and H1299). The antibodies give good signal at about 300 kDa, but have a little bit of non-specific binding at about 100 kDa. For detection of SETD2 with these antibodies I used regular western blot protocol for high molecular weight proteins (8% PAAG and wet transfer overnight). Antibodies work well for overnight incubation +4C, and room temperature incubation for 1.5-2 h. I can recommend these antibodies! Few companies make antibodies for this protein.
Review Date: 28 Jul 2020 | ABclonal Technology
Applications
Antibody Overview
About the company
ABclonal Technology
Based in Massachusetts, ABclonal is a rapidly growing bio-solutions provider and custom reagents manufacturer. Our catalog lists 10,000+ self-manufactured antibodies, ELISA kits, enzymes, and more that can help life science researchers study crucial areas, including Cancer, Epigenetics, DNA Damage & Repair, Infectious Diseases among others. In stock products are shipped next day.