MOUSE ANTI RABBIT GAPDH
Mouse anti Rabbit GAPDH antibody, clone 6C5 recognizes glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a ~36 kDa multifunctional protein whose main function is to catalyse the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate, in conjunction with inorganic phosphate and nicotinamide adenine dinucleotide (NAD). This reaction is an important energy yielding step in carbohydrate metabolism. GAPDH has also been shown to translocate to the nucleus under a variety of stressors, most of which are associated with oxidative stress, whereby it mediates cell death. A further report has shown that GAPDH binds to several proteins that are responsible for neurodegenerative diseases, such as amyloid precursor protein and Huntingtin (Hara et al. 2006).
Product Details
- Cat. No.
- MCA4739
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
Staining of HeLa whole cell lysate with Mouse anti Rabbit GAPDH:Dylight®800
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Reviews
Performs well without variability.
Western blot
This a good antibody. High specificity and reproducibility. It is also very easy to use
Review Date: 30 Oct 2020 | Bio-Rad
Applications
- ELISA (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (Frozen Sections) (IHC (Fr))
- Immunoprecipitation (IP)
- Western Blotting (WB)
Antibody Overview
About the company
Bio-Rad
Bio-Rad Laboratories, Inc. is a multinational manufacturer and distributor of life science research products, clinical diagnostics, and analytical instrumentation, based in Hercules, California. The company serves more than 70,000 research and industry customers worldwide through a network of more than 30 wholly owned subsidiary offices.