HLA DRA Antibody
Product Details
- Cat. No.
- NBP2-45043
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
![Flow Cytometry: HLA DRA Antibody (169-1B5.2) [NBP2-45043] - A surface stain was performed on human peripheral blood lymphocytes with HLA DRA (169-1B5.2) antibody NBP2-47722APC and a matched isotype control NBP2-27231APC. Cells were incubated in an antibody dilution of 0.5 ug/mL for 20 minutes at room temperature. A co-stain was performed with NBP2-26646. Image using the Allophycocyanin form of this antibody.](https://cdn.sanity.io/images/f5b6mtfn/antibodies-prod/adc31ffd757230a30001a00f795c7421b72221d5-219x400.jpg?w=1080&q=75&fit=clip&auto=format)
Flow Cytometry: HLA DRA Antibody (169-1B5.2) [NBP2-45043] - A surface stain was performed on human peripheral blood lymphocytes with HLA DRA (169-1B5.2) antibody NBP2-47722APC and a matched isotype control NBP2-27231APC. Cells were incubated in an antibody dilution of 0.5 ug/mL for 20 minutes at room temperature. A co-stain was performed with NBP2-26646. Image using the Allophycocyanin form of this antibody.
![Flow Cytometry: HLA DRA Antibody (169-1B5.2) [NBP2-45043] - A surface stain was performed on human peripheral blood lymphocytes with HLA DRA (169-1B5.2) antibody NBP2-47722APC and a matched isotype control NBP2-27231APC. Cells were incubated in an antibody dilution of 0.5 ug/mL for 20 minutes at room temperature. A co-stain was performed with NBP2-26646. Image using the Allophycocyanin form of this antibody.](https://cdn.sanity.io/images/f5b6mtfn/antibodies-prod/adc31ffd757230a30001a00f795c7421b72221d5-219x400.jpg?w=256&q=75&fit=clip&auto=format)
The supplier does not provide quotations for this antibody through SelectScience. You can search for similar antibodies in our Antibody Directory.
Description
This antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Bovine, Cat (Feline), Human
- Clone: 169-1B5.2
- Isotype: IgG2b Kappa
Handling
- Storage: Store at 4°C.
- Buffer: 10mM PBS and 0.05% BSA
- Specificity: 5
Applications
- Flow Cytometry (FC)
- Immunocytochemistry (ICC)
- SDS-PAGE (SDS-PAGE)
Performs well.
Flow cytometry
Antibody did what was intended. Was useful in showing MHCII+ cells in the sample.
Review Date: 5 Sept 2018 | Novus Biologicals, LLC
![Flow Cytometry: HLA DRA Antibody (169-1B5.2) [NBP2-45043] - A surface stain was performed on human peripheral blood lymphocytes with HLA DRA (169-1B5.2) antibody NBP2-47722APC and a matched isotype control NBP2-27231APC. Cells were incubated in an antibody dilution of 0.5 ug/mL for 20 minutes at room temperature. A co-stain was performed with NBP2-26646. Image using the Allophycocyanin form of this antibody.](https://cdn.sanity.io/images/f5b6mtfn/antibodies-prod/adc31ffd757230a30001a00f795c7421b72221d5-219x400.jpg?w=3840&q=75&fit=clip&auto=format)