GPR177, Polyclonal Antibody
GPR177, also known as Wntless (WLS) or Evi, is an evolutionarily conserved transmembrane protein necessary for Wnt protein secretion. GPR177 localizes to compartments of the secretory pathway, including the ER, Golgi apparatus, endosomes, and plasma membrane. GPR177 is overexpressed in several cancer types including glioma and gastric cancer. Several isoforms of GPR177 exist due to the alternative splicing, with predicted MW around 62 and 51 kDa, respectively. The sequence can be processed by removing the signal peptide, which generates a mature form of 45-46 kDa. In addition, slow migragrating band above 62 kDa can also be detected because GPR177 is modified by N-linked glycosylation (PMID: 20549736).
Product Details
- Cat. No.
- MBS769833
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Reviews
Performs well.
Western blot, immunogold
We got reproducible results that were very specific, we got a strong signal in WB (1/300; 30 ug protein).
Review Date: 2 May 2020 | MyBioSource
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
- Western Blotting (WB)
Antibody Overview
About the company
MyBioSource
Founded originally in Vancouver, British Columbia in 2006 by three enthusiastic scientists passionate about providing the best biological reagents worldwide, MyBiosource, Inc. was incorporated as a company with big visions. Since 2007, we have relocated our headquarters to sunny Southern California, San Diego (USA).
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