ARL13B Antibody
ARL13B, also named as ARL2L1, is a small ciliary G protein of the Ras superfamily. Localized in the cilia, it is required for cilium biogenesis and sonic hedgehog signaling. Defects in ARL13B are the cause of Joubert syndrome (JS) which is an autosomal recessive disorder characterized by a distinctive cerebellar malformation (PMID: 19906870).This antibody detects two specific bands at 60 kDa and 48 kDa. Arl13b is predicted to be a 48 kDa protein, and the 60 kDa band is likely to represent a modified form of Arl13b. ARL13B can be used to mark the cilia (PMID:22072986).
Product Details
- Cat. No.
- 17711-1-AP
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Immunofluorescent analysis of ( 4% PFA ) fixed MDCK cells using 17711-1-AP(ARL13B antibody) at dilution of 1:100 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Reviews
This antibody reliably works great!
Immunofluorescence and WB
This antibody works great with little background. IF 1:100 WB 1:1000
Review Date: 30 Aug 2018 | Proteintech Group
Applications
- ELISA (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
- Western Blotting (WB)
Antibody Overview
About the company
Proteintech Group
Proteintech is a manufacturer and supplier of polyclonal and monoclonal primary antibodies, plus an expanding range of sandwich ELISA kits. All its products are made and validated in-house by its own scientists using endogenous, unmodified samples as standard. Proteintech’s antibodies and ELISA kits are only available through it and its approved distributors as it believes transparency and traceability is key to providing quality reagents. It also provides 24 hour technical support and covers all products with a guarantee policy that returns grant money and not credit. In continuing to uphold its validation, supply and customer service ethics, Proteintech assumes ultimate responsibility for the quality of its products and their performance at the lab bench. Furthermore, it demonstrates Proteintech team’s dedication to its customers’ research.