Avoid antigen excess with the Optilite Analyzer

11 April 2024

Antigen excess, also known as 'prozone' or 'hook effect', occurs when antigen levels are so high that they hinder antigen-antibody crosslinking. This leads to the formation of smaller immune complexes, causing immunoassays to underestimate high protein concentrations. Binding Site highlights the Optilite® Analyzer and how its software can utilize one of three different antigen excess detection methods when required during assay design. The Optilite features optimized antigen excess protection, preventing falsely low or false negative results and is a reliable and efficient solution for diagnostic testing.