Adapted 3D Cell Culture Assays for Improved Drug Response Modelling

4 May 2017

In this video, Dr. Anne Hammerstein, field applications scientist at TTP Labtech, discusses the renewed interest in 3D cell culture models and the challenges that need to be met in order to adapt these models for high throughput and high content screening. The high rate of attrition in the cancer drug discovery process is, in part, due to failure of 2D in vitro cell culture models to predict drug responses of tumors in vivo. This is driving interest in more physiologically relevant in vitro models, such as tumor spheroids and colonies.