TechTalk: Overcoming barriers in expressing challenging proteins with advanced expression systems

Friday, July 31 at 16:30 BST | 17:30 CEST | 11:30 EDT | 08:30 PDT

Join this TechTalk to discover practical strategies for improving the expression of next-generation biologics that can be difficult to produce using conventional transient expression systems. Learn how advanced mammalian expression technologies can support recombinant protein production, from gene synthesis and optimization through expression, purification, and characterization.

The session will highlight how the new Thermo Fisher Scientific Expi293™ PRO and ExpiCHO™ K1 PRO Expression Systems can help improve yields for monoclonal antibodies, bispecific and multispecific antibodies, and other challenging recombinant proteins. Attendees will also explore how integrated workflows and early developability assessment can help reduce development risk and accelerate therapeutic candidate progression.

This TechTalk will be presented by Thermo Fisher Scientific experts, who will share practical insight into overcoming low protein expression, streamlining biologics development workflows, and improving the efficiency of therapeutic protein production.

Certificate of attendance
If you attend the live TechTalk, you will automatically receive a certificate of attendance, including a learning outcomes summary, for continuing education purposes. If you view the on-demand TechTalk, you can request a certificate of attendance by emailing editor@selectscience.net.

TechTalk details

  • Cost: Free to attend
  • Location: Online
  • Duration: 20 minutes

Registration is required to secure your place. If you register but can’t attend live, you will receive a link to the on-demand recording once it becomes available.

Speakers

Dr. Jonathan Zmuda
Dr. Jonathan Zmuda
Speaker
Senior Director, R&D, Protein & Viral Vector Expression Systems, Thermo Fisher Scientific
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Who should attend?

This event is perfect for:
  • Scientists working in recombinant protein expression and production
  • Biotherapeutic and antibody discovery researchers
  • Cell line development and protein engineering specialists
  • Process development specialists
  • Translational and preclinical research teams
  • Academic and industry researchers developing complex recombinant proteins

Gibco Expi293 PRO Expression System

Thermo Fisher Scientific

The Gibco™ Expi293™ PRO Expression System is a next-generation transient mammalian expression platform designed to maximize protein yields while reducing timelines. Optimized for difficult-to-express proteins, monoclonal antibodies, and complex biologics, it delivers robust, scalable performance to accelerate protein production, developability studies, and therapeutic research.

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What will this webinar cover?

Key learning objectives:

  • Understand common causes of low protein expression and strategies to overcome them using advanced transient mammalian expression systems.
  • Learn how integrated workflows can streamline recombinant protein production from gene synthesis through characterization.
  • Discover how Expi293™ PRO and ExpiCHO™ K1 PRO Expression Systems improve yields for difficult-to-express proteins compared with legacy systems.
  • Explore approaches that support early developability assessment to accelerate therapeutic candidate progression.

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