TechTalk: Clear the noise for better chromatographic separation of GLP‑1 receptor agonists and insulin impurities

Friday, June 12 at 14:00 BST | 15:00 CEST | 09:00 EDT | 06:00 PDT

In the race to launch GLP‑1 generics and novel agonists, complex impurity analyses can directly impact your speed to market. Conventional columns often obscure peaks of critical impurities, leading to costly rework and increased regulatory scrutiny.

Join this SelectScience^® TechTalk and discover new analytical tools designed to streamline your process and deliver reproducible, high-resolution separations of GLP‑1 receptor agonists (GLP-1 RAs) and insulin-related impurities – without relying on suppressive mobile‑phase additives. Michael Zagieboylo, Principal Product Manager at Waters Corporation, will share how improved resolution can accelerate method development, increase confidence in your results, and support faster time to market for your GLP-1 RA and insulin products.

Certificate of attendance
If you attend the live TechTalk, you will automatically receive a certificate of attendance, including a learning outcomes summary, for continuing education purposes.

If you view the on-demand TechTalk, you can request a certificate of attendance by emailing editor@selectscience.net.

TechTalk details

Cost: Free to attend
Location: Online
Duration: 20 minutes

Registration is required to secure your place. If you register but can’t attend live, you will receive a link to the on‑demand recording once it becomes available.

Speakers

Michael Zagieboylo

Speaker

Principal Product Manager, Waters Corporation

Who should attend?

This event is perfect for:

Analytical development scientists
Process development scientists
Chief Experience Officer (CXO)
GLP-1 researchers

Featured products

Request Quote for All Products

AccQ•Tag and AccQ•Tag Ultra Amino Acid Chemistries
Waters
Amino Acid Analysis Columns
(2)
Empower Software
Waters | Wyatt Technology
Empower™ Software Solutions supports the collection, processing, and reporting of data from DAWN™ multi-angle light scattering (MALS) and Optilab™ differential refractive index (RI) instruments.
(0)
ACQUITY UPLC System
Waters
Waters ACQUITY UPLC - Dramatic Improvements in Speed, Sensitivity and Resolution Whether you work in methods development or quality assurance, in drug discovery and development or testing for safety in food supplies, you seek a productivity edge. With the ACQUITY UPLC® System, now you can get more information in a single, short run than you've ever seen with HPLC. Waters ACQUITY UPLC System UltraPerformance LC® (UPLC®) technology starts with unique 1.7 μm small-particle chemistries. Chromatographers no longer need to choose between speed and resolution–with UPLC you get both. Instrument Designed for Chemistry; Chemistry Designed for the Instrument The ACQUITY UPLC System has been holistically designed to match the performance needs of our innovative column chemistries with robust hardware, easy-to-use software and specialized support services. Small, pressure-tolerant particles High-pressure fluidic modules Minimized system volume Negligible carryover Reduced cycle times Fast response detectors Integrated system software and diagnostics With UPLC you have the ability to work more efficiently with higher speed, sensitivity and resolution at a much wider range of linear velocities, flow rates and backpressures to obtain superior results. The Waters ACQUITY UPLC System's high-pressure fluidics optimizes flow rates to make the most of small particle technology. The ACQUITY UPLC System's sample-handling design is designed to ensure exceptionally low carryover and reduced cycle time. And when interfaced with the Sample Organizer, it increases unattended sample capacity by ten times. High-speed detectors, both optical and mass, contribute to increased sensitivity and help manage the heightened speed and resolution requirements of UPLC. ACQUITY UPLC Systems are easily controlled, diagnosed, and monitored via a graphical system console interface. The console offers: Quick and easy access to critical instrument parameters Simple system start-up, elegant system status monitoring and predictive performance indicators to ensure maximum productivity Data management capabilities that are supported by both MassLynx™ and Empower™ software The ACQUITY UPLC System is also supported by Intelligent Device Management technology with our Connections® INSIGHT™ service, providing instrument diagnostics.
(167)
ACQUITY UPLC Peptide CSH Columns
Waters
Reversed-Phase Peptide Columns
(1)
ACQUITY Premier Columns
Waters
ACQUITY Premier Columns with MaxPeak High-Performance Surface (HPS) technology reduce analyte/surface interactions.
(8)

What will this webinar cover?

How to gain greater resolution for your GLP-1 RA and insulin impurity analysis separations
How to achieve up to 3x faster separations
How to identify subtle impurities, such as single amino-acid substitutions and deamidation, beyond the detection limits of conventional reversed-phase technologies

Links

Waters Company website

Tags

Protein Purification Reversed-Phase Chromatography Quality Control Insulin Protein Characterization Peptides

ACQUITY UPLC System

Waters

Waters ACQUITY UPLC - Dramatic Improvements in Speed, Sensitivity and Resolution Whether you work in methods development or quality assurance, in drug discovery and development or testing for safety in food supplies, you seek a productivity edge. With the ACQUITY UPLC® System, now you can get more information in a single, short run than you've ever seen with HPLC. Waters ACQUITY UPLC System UltraPerformance LC® (UPLC®) technology starts with unique 1.7 μm small-particle chemistries. Chromatographers no longer need to choose between speed and resolution–with UPLC you get both. Instrument Designed for Chemistry; Chemistry Designed for the Instrument The ACQUITY UPLC System has been holistically designed to match the performance needs of our innovative column chemistries with robust hardware, easy-to-use software and specialized support services. Small, pressure-tolerant particles High-pressure fluidic modules Minimized system volume Negligible carryover Reduced cycle times Fast response detectors Integrated system software and diagnostics With UPLC you have the ability to work more efficiently with higher speed, sensitivity and resolution at a much wider range of linear velocities, flow rates and backpressures to obtain superior results. The Waters ACQUITY UPLC System's high-pressure fluidics optimizes flow rates to make the most of small particle technology. The ACQUITY UPLC System's sample-handling design is designed to ensure exceptionally low carryover and reduced cycle time. And when interfaced with the Sample Organizer, it increases unattended sample capacity by ten times. High-speed detectors, both optical and mass, contribute to increased sensitivity and help manage the heightened speed and resolution requirements of UPLC. ACQUITY UPLC Systems are easily controlled, diagnosed, and monitored via a graphical system console interface. The console offers: Quick and easy access to critical instrument parameters Simple system start-up, elegant system status monitoring and predictive performance indicators to ensure maximum productivity Data management capabilities that are supported by both MassLynx™ and Empower™ software The ACQUITY UPLC System is also supported by Intelligent Device Management technology with our Connections® INSIGHT™ service, providing instrument diagnostics.

(167)

Speakers

Who should attend?

Featured products

AccQ•Tag and AccQ•Tag Ultra Amino Acid Chemistries

Empower Software

ACQUITY UPLC System

ACQUITY UPLC Peptide CSH Columns

ACQUITY Premier Columns

What will this webinar cover?

Links

Tags

Register for free

AccQ•Tag and AccQ•Tag Ultra Amino Acid Chemistries

Empower Software

ACQUITY UPLC System

ACQUITY UPLC Peptide CSH Columns

ACQUITY Premier Columns