How to deliver efficient, consistent high-throughput oligonucleotide synthesis in-house
Tuesday, December 8 at 16:00 GMT | 17:00 CET | 11:00 EST | 08:00 PST
High-throughput oligonucleotide synthesis is increasingly important for screening therapeutic candidates and producing the diverse primers, probes and adapters required for personalised sequencing workflows. Yet scaling output is not simply about increasing the number of synthesis positions. Laboratories must also manage solid-support consistency, reagent use, fluid delivery and changing requirements for formats, scales and chemistries.
If you are considering bringing oligonucleotide synthesis in-house or expanding an existing operation, join our experts for a practical discussion of the factors that determine efficiency and consistency at high throughput.
We will explore how solid-support design, plate format and instrument configuration work together to support reliable small-scale synthesis of up to 768 oligos in a single run.
Certificate of attendance
If you attend the live webinar, you will automatically receive a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
If you view the on-demand webinar, you can request a certificate of attendance by emailing editor@selectscience.net.
Webinar details
Cost: Free to attend
Location: Online
Duration: 60 minutes
Registration is required to secure your place. If you register but can’t attend live, you will receive a link to the on‑demand recording once it becomes available.
Speakers
Who should attend?
- Scientists screening ASO, siRNA and other oligonucleotide candidates
- Process-development and R&D scientists establishing in-house synthesis
- Oligonucleotide manufacturers and service providers expanding throughput
- Developers of personalised sequencing panels, including tumour-informed MRD workflows
- Teams producing primers, probes, adapters or barcodes in large numbers
- Laboratory and production managers evaluating high-throughput synthesis platforms
What will this webinar cover?
Key learning objectives:
- Why consistently loading loose controlled pore glass becomes more difficult at small synthesis scales
- How fritted CPG can improve support uniformity, flow and reagent efficiency
- How reagent contact, agitation and flow control influence high-throughput synthesis
- Identify the key considerations when selecting synthesis formats and instrument configurations for high-throughput oligonucleotide production
Join the webinar to get answers to these questions:
- Why is consistently loading loose controlled pore glass harder at small synthesis scales?
- How can fritted CPG improve support uniformity, flow and reagent efficiency?
- How do reagent contact, agitation and flow control affect high-throughput synthesis?
- What should you consider when selecting synthesis formats and instrument configurations?
- How can solid-support design, plate format and instrument setup enable reliable synthesis of up to 768 oligos per run?