What is cytokine release syndrome?

Cytokine release syndrome (CRS) arises from an excessive activation of both the innate and adaptive immune systems, leading to an overabundance of cytokines, substances capable of influencing other cells. It can be triggered by a variety of factors, such as the presence of certain tumors, infectious diseases, or the administration of therapies including bispecific antibodies or adoptive cell transfer. Delve into the intricate mechanisms underlying CRS and discover an innovative platform from The Jackson Laboratory that is designed to predict CRS.