Pure excellence chromatography systems for high‑performance purification and separation
5 Jun 2026
This video showcases the Pure Excellence Chromatography Systems from BÜCHI, designed to streamline purification workflows in chemical research and development. Discover how the platform combines intuitive software, automated sample handling, and advanced separation capabilities to deliver high purity and reproducibility. With flexible gradient control, evaporative light scattering detection (ELSD), and built-in safety features, the system enables efficient, high-performance purification while reducing user error and improving workflow reliability.
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Video transcript
Show transcript
In modern chemical research and development, purification is often one of the most time-consuming and critical steps in the workflow. Obtaining high purity and consistent reproducibility can be challenging, particularly when dealing with a complex mixture.
To address these challenges, the Pure Excellence Chromatography Systems introduce a new generation of high-performance separation solutions designed to deliver an effortless user experience, powerful technology, and enhanced safety features.
Here are its main key benefits:
First, the system has been designed with the user in mind. It features intuitive software that simplifies operation, a quick-release cartridge holder that securely holds the cartridge in place with just one hand, and automated sample injection that saves time while reducing user error.
The system also delivers powerful technology for complex separations, enabling purification with exceptional resolution and purity through precise ELSD detection with low sample consumption. It offers flexible gradient capability, supporting up to four solvents at the same time, and high-performance pumps that ensure highly pure separations.
Finally, it has been designed to reduce risk and boost confidence. The system ensures safe operation with active ventilation to limit fume exposure, RFID tracking to minimize user error, and sensors to monitor leaks, overpressure, solvent levels, and waste levels for enhanced safety.
Now that you have seen the key benefits, let me show you just how easy it is to run a separation with the Pure Excellence Chromatography System in practice.
Place the solvent lines into the bottles, then prime and calibrate the instrument. With just a few clicks, the instrument is ready to go.
Go to the chromatography menu in the software and define your parameters in four steps:
- Step one: Select your flash cartridge from the list.
- Step two: Define your solvent and gradient. This can be done in a table or directly on a graph.
- Step three: Define your detection parameters. With just one click, you can activate ELSD.
- Step four: Define your parameters for fraction collection and insert the racks.
Tap the start button.
Define the type of sample loading. This can be liquid or solid, before or after equilibration.
Install your flash cartridge. Inject your liquid sample or connect your solid loader.
Interact with the software during the run, making real-time adjustments or using zoom-in features.
Review the results and compare them with previous runs.
And that’s all — easy and intuitive steps to achieve high-performance separation.
Switch to the Pure Excellence Chromatography System and enjoy unmatched versatility.
To discover more, visit our website or contact us today.
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Pure Excellence Chromatography System
BUCHIDesigned with users in mind, the C-905, C-910, and C-915 models provide the most powerful flash chromatography capabilities and flexible detection options, including ELSD, while the C-950 also integrates prep HPLC for greater versatility.
