Top List: 5 top resources for mycotoxin quantitation in cannabis samples

A compilation of useful materials for quantifying mycotoxins in cannabis products, necessary to meet industry standards and reduce potential health risks from contamination

10 Jan 2020

Whilst the cultivation conditions for cannabis are tailored to support the growth of the plant, they often provide an ideal environment for the production of potentially pathogenic molds and fungi such as Aspergillus. Storage, transportation and processing are also conducive to contamination and, in combination, can lead to sufficiently concerning levels of chemical mycotoxin production. 

Many mycotoxins, such as the aflatoxins G1, G2, B1, B2, or ochratoxin A, have been highlighted as immunosuppressive, carcinogenic, neurologically toxic, and hepatotoxic. Even the Aspergillus mold itself can cause lung infections such as aspergillosis. Therefore, considering the great risk to consumer health, the development of accurate testing methods is of utmost importance to the industry. 

Here, we’ve collated some of the latest content and innovations in this field to aid scientists in the quantification of these harmful molds and their secondary metabolites, including liquid chromatography, real-time PCR, UPLC-MS/MS and GC-MS/MS.

Application note: Quantitation of aflatoxins in cannabis by liquid chromatography

Shimadzu presents a study that focuses on developing a powerful detection method, using the Prominence-i and the RF-20Axs Fluorescence Detector, that allows cannabis testing labs to confidently report concentrations below regulatory limits, including aflatoxins B1, B2, G1 and G2 combined to 20 ppb and 20 ppb for ochratoxin A alone. 

Application note

Industry news: Bio-Rad launches kit for detection of hazardous molds in cannabis products

Bio-Rad Laboratories, Inc. has announced the launch of the iQ-Check Aspergillus Real-Time PCR Kit, a fast and accurate method for detecting four potentially hazardous molds — Aspergillus flavus, A. fumigatus, A. niger, and A. terreus — in cannabis and cannabis-infused products.

The Scientists' Channel: Essential quality control assessments for cannabis

In this video, Dr. Jonathan Speare explains how White Buffalo Laboratories tests cannabis for pesticides and mycotoxins to provide a safe product and discusses quality assurance requirements and how quantifying marijuana testing is changing the cannabis industry.

Application note: Analysis of residual pesticides and mycotoxins in cannabis to meet Californian regulations

Jonathan Speare

In this application note, Waters presents the use of a simple sample extraction and dispersive solid phase extraction (dSPE) clean-up where the extract is analyzed by UPLC-MS/MS and/or GC-MS/MS for rapidly monitoring pesticides and mycotoxins in cannabis matrix. 

Editorial article: Cannabis testing: The need for robust methods and true transparency

In this exclusive interview, we hear from Petra Erlandson of Alkemist Labs about the need for transparent and universal protocols in botanical testing. Erlandson also reveals the key technologies that enable the team at Alkemist to test different material types and product matrixes reliably and accurately — and the importance of finding a manufacturer you can partner with effectively.


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