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Welcoming more than 250 delegates and over 70 prestigious moderators and panelists, Pharma Integrates takes place on 15-16 November at the Grange City Hotel, London

SB000 reverses cellular ageing as measured by DNA methylation clocks in multiple cell types without loss of cellular identity or signs of pluripotency

New agreement brings leaders in biomedical knowledge solutions and knowledge graph technologies together to aid the biopharmaceutical industry in analytics-driven drug discovery

Brand: PYREX®

We have teamed up with the National Institute of Biomedical Innovation to bring you access to over 1,600 cell lines as the exclusive provider of JCRB's comprehensive catalog of cell lines in Europe.

Intended for the assay of recombinant B-Raf (supplied) kinase activity with experimental variables as determined by the user. For assay of B-Raf activity from a cell lysate, we recommend an immunoprecipitation-kinase assay, using anti-B-Raf antibody (07-453).

Intended for the assay of recombinant Raf-1 (supplied) kinase activity, with experimental variables as determined by the user. For assay of Raf-1 activity from a cell lysate, we recommend an immunoprecipitation-kinase assay, using anti-Raf-1 antibody (07-396).

We have applied CompoZr Zinc Finger Nuclease technology to create an unparalleled range of genetically modified mammalian cell lines for use in areas, such as target validation, drug discovery and drug development.

A pre-engineered cell line with integrated genetic elements for simple payload exchange of your specific promoter and gene of interest. The landing pad construct is targeted to the AAVS1 safe harbor locus with a fluorescent marker for downstream screening.

The MISSION pLKO.1-puro Control Vector is a lentivirus plasmid vector. The vector does not contain an shRNA insert and is useful as a negative control in experiments using the MISSION shRNA library clones.

Human CRISPRi Kinase Phosphatase Drug Targets Kit contains 2 sub-pools of top 5 gRNAs per gene as well as a separate sub-pool of 5 supplemental gRNAs per gene for increased sensitivity and includes non-targeting controls built in.

R&D Proteome Profiler Human Phospho-Kinase Array Kit - Human Phospho-Kinase Array Kit for the parallel determination of the relative levels of protein phosphorylation. The kit contains 4 sets of 2 membranes - each spotted in duplicate with 46 different kinase antibodies. The R&D Human Phospho-Kinase Array is a rapid, sensitive, and economical tool to simultaneously detect the relative levels of phosphorylation of 46 kinase ph…

The CardioExcyte 96 is a 96 well plate-based hybrid device supporting highly resolved impedance-based measurements and electric field potential recordings. It analyses the contractility and electrophysiology of cellular cardiac networks, as well as morphological changes, e.g. cytotoxic responses, of non-contractile cells such as hepatocytes, cancer cells, cell lines or stem cells.

F(ab')2 fragments of antibodies are generated by pepsin digestion of whole IgG antibodies to remove most of the Fc region while leaving intact some of the hinge region. Used for specific applications, such as to avoid binding of antibodies to live cells with Fc receptors or to Protein A or Protein G. 

Fab fragment antibodies are generated by papain digestion of whole IgG antibodies to remove the entire Fc portion, including the hinge region. Block endogenous immunoglobulins on cells, tissues , or other surfaces. Block exposed immunoglobulins in multiple labeling experiments using primary antibodies from the same species. Fab-label primary antibodies in solution without compromising activity.