Using the Tecan AC Extraction Plate™ for Sample Preparation
23 Mar 2015In this technical note, a screening study was undertaken to examine a range of different analytes with varying functional groups and molecular sizes. The target molecules were pharmaceuticals, pesticides, or simple stereotypical organic molecules. An extraction step was performed in different solvent mixtures composed of water and an organic solvent. Comparison of the analyte concentration in the supernatant before and after extraction yielded the extraction efficiency.
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AC Extraction Plate™
TecanThe Tecan AC Extraction Plate* with TICE™ (Tecan Immobilized Coating Extraction) technology revolutionizes your sample preparation routine. The AC Extraction Plate is a 96-well, deep-well microplate, with each well having a proprietary TICE™ coating. TICE is a material with distinct absorptive properties, and this coating efficiently extracts specific small molecule analytes from aqueous solutions, releasing them when in contact with a suitable organic solvent. A simple pipette and shake sequence, with no filtration, centrifugation or solvent evaporation, is all that is required. The AC Extraction Plate is easily integrated into automated processes, making it a perfect match with Tecan’s Freedom EVO® liquid handling platform. AC Extraction Plate™ Features: Cost-effective – Simple pipette and shake workflow, without labor intensive centrifugation, filtration and solvent evaporation steps. Convenient and fast – Just unpack and start, no conditioning or other preparations needed. Highly reproducible – Pipette and shake routines are easily standardized and automated on a liquid handling platform, eliminating random errors and increasing consistency of results. * For research use only – not for clinical diagnostic applications