TRPM7 activation by internal sequestering of Mg2+ ions recorded on the Port-a-Patch®

9 Feb 2011

This application note presents data recorded on the Port-a-Patch® with internal perfusion showing recordings of mouse TRPM7 (mTRPM7) and block of this channel by the internal perfusion of Mg2+ ions.

Port-a-Patch

Nanion Technologies GmbH

The Port-a-Patch is a miniaturized semi-automated patch clamp system supporting giga-seal recordings from one cell at a time. It offers fast and easy access to patch clamp data with only minimal training. Not only a powerful research tool but also ideal for educational purposes and quick tests of cells and ion channels.

(7)

Links

Tags

ElectrophysiologyElectrophysiology is the study of biological voltage changes, from a single ion channel through to a whole organ scale. Voltages can be measured using patch clamping, automated workstations, electrophysiology rigs or cell based assays. Specific cell lines, manipulators and microinjectors are also available for electrophysiology research.
TRPM7 activation by internal sequestering of Mg2+ ions recorded on the Port-a-Patch®