ResourceSpectroscopy

The Importance of High Glass Quality for Detecting Low Concentrations of Analytes

15 Nov 2018

In this application note, drugs (e.g. Doxepin, Clomipramin, Bromperidol (containing trisubstituted N-atoms = tertiary amines and other TCA´s) have been investigated in serum in order to see the effects of certain glass qualities. The results are reported by reproducibility data using different types of 2 mL autosampler glass vials.

Thermo Scientific™ UltiMate™ 3000 UHPLC system

Thermo Fisher Scientific

  The Thermo Scientific™ UltiMate™ 3000 HPLC system offers UHPLC compatibility across all modules, ensuring maximum performance. Covering flows from 20 nL/min to 10 mL/min and offering a wide range of pumping, sampling, and detection modules, the UltiMate 3000 series provides solutions for all your chromatography needs. UltiMate 3000 HPLC system Features & Benefits:   UHPLC design for all nano, standard analytical, and RSLC systems. 620 bar maximum pressure for basic and standard analytical systems—setting a new benchmark in HPLC. x2 Dual Systems form a unique platform for routine analysis, increased productivity solutions, and advanced chromatographic techniques. Systems are controlled using Thermo Scientific™ Chromeleon™ Chromatography Data System software—providing Intelligent Functionality and Operational Simplicity™. Systems are offered with Thermo Scientific™ Viper™ and Thermo Scientific™ nanoViper™ fitting systems—fingertight, zero-dead-volume connections even at UHPLC pressures.

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Thermo Scientific™ Q Exactive™ GC Orbitrap™ GC-MS/MS System

Thermo Fisher Scientific

The Thermo Scientific™ Q Exactive™ GC system is the first-ever combination of high resolution gas chromatography with high-resolution/accurate-mass (HR/AM) Orbitrap detection for the most comprehensive sample characterization. This easy-to-use system provides the most comprehensive characterization of samples in a single analysis for the highest confidence in compound discovery, identification, and quantitation. Building upon the flexible modularity of the Thermo Scientific™ TRACE™ 1300 Series GC, including user-exchangeable injectors and detectors, the Q Exactive GC system has the quantitative power of a GC triple quadrupole MS combined with the high precision, full scan high-resolution/accurate-mass capability that only Orbitrap technology can offer.   Key Features: Advanced quadrupole technology (AQT) for high transmission of selected masses Resolving power up to 120,000 at m/z 200 Part-per-trillion-level sensitivity Thermo Scientific™ Extractabrite™ ion source for robust, rugged electron impact (EI) and chemical ionization (CI) performance Curved linear C-trap for precise ion injection HCD collision cell for higher energy collisional dissociation provides MS/MS ion characterization Intelligent identification software elucidates the nature of each injected sample. Applications: Untargeted and targeted metabolomics Food and beverage Industrial analyses Environmental Pharmaceutical Clinical and toxicology

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Thermo Scientific™ Hypersil GOLD™ C18 Selectivity LC Columns

Thermo Fisher Scientific

Achieve exceptional peak shape and resolution for your HPLC and LC/MS applications with Thermo Scientific™ Hypersil GOLD™ HPLC columns. These endcapped, ultrapure, silica-based columns deliver significant reduction in peak tailing using generic gradients with C18 selectivity. With their excellent resolution, efficiency, and sensitivity, Hypersil GOLD columns give you confidence in the accuracy and quality of your analytical data.

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