Selecting HPLC columns: Going under the hood

The unique properties of Epic™ Naphthyl places its selectivity between graphitized carbon and alkyl type stationary phases. Epic Naphthyl is a naphthalene-based material, with high bonding density and exhibits strong π-π interaction and charge transfer interactions and performs well for diastereomer separations and non-polar compounds. Epic HPLC and UHPLC columns are compatible with a wide range of organic modifiers and buffers and stable over a wide pH range.

Under highly aqueous conditions, our novel proprietary bonding chemistry allows the bonded chains to remain fully extended in the mobile phase. Epic™ Polar can retain highly water-soluble compounds such as small organic acids, water-soluble vitamins, purines and pyrimidines, catecholamines and other polar compounds. The Epic Polar column offers improved polar compound retention under RP conditions which has been further refined with extensive selectivity options.

The Epic™ line of LC columns is based on high density monomerically bonded phases produced through a proprietary bonding process. Epic HPLC columns are compatible with a wide range of organic modifiers and buffers and stable over a wide pH range. All Epic products use an ultra-high purity metal free silica and undergo strict quality control testing. For flexibility, we offer a wide range of column sizes as well being fully scalable from analytical to preparative dimensions.