Sample digestion for AOF determination according to EPA Method 1621

Per‑ and polyfluorinated alkyl substances (PFAS) are persistent 'forever chemicals' that accumulate in water, soil, organisms, and the food chain, creating an urgent need for sensitive, reliable monitoring. Yet the vast diversity of PFAS compounds and their widespread distribution make comprehensive detection difficult.

Discover why the adsorbable organically bound fluorine (AOF) sum parameter has become an essential screening tool, and understand the principles behind its determination, including adsorption, high‑temperature pyrohydrolysis, and ion chromatography. Plus, explore how flexible digestion systems, such as the ICprep, support accurate AOF analysis in line with EPA Method 1621, helping laboratories strengthen PFAS surveillance programs.