ResourceLife Sciences
Saliva preparation for rare tumor cell analysis workflow
17 Nov 2025Detecting circulating tumor cells (CTCs) in head and neck squamous cell carcinoma (HNSCC) has long been a challenge. Low prevalence, diverse morphology, and reduced EpCAM expression all make detection difficult.
Together with Thomas Jefferson University, Bio-Rad has developed a streamlined liquid biopsy workflow using saliva to simplify rare tumor cell analysis.
Powered by the Genesis Cell Isolation System and Celselect Slides™ Technology, this new approach enriches and enumerates CTCs with greater efficiency. By using size-based selection, Bio-Rad helps overcome low yields and EpCAM variability, delivering clearer insights for cancer research.
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The Genesis System
Bio-RadCelselect™ Slides capture and isolate individual rare cells, or CTCs based on their size
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Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Liquid BiopsiesLiquid biopsies are non-invasive tests used to detect cancer and other diseases by analyzing blood or other bodily fluids. This technique is gaining popularity for early detection, monitoring treatment response, and detecting minimal residual disease. Explore liquid biopsy solutions in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Cancer DiagnosticsThere are a wide variety of diagnostic tests for cancer available, and this range continues to expand as our knowledge of cancer improves. Current diagnostic methods include biopsy, imaging and blood tests for known biomarkers. New methods in research development include liquid biopsies and cancer breathalyzers.Single Cell AnalysisSingle-cell analysis involves studying individual cells to gain insights into their behavior, gene expression, and function. This approach is valuable in cancer research, stem cell biology, and immunology. Explore single-cell analysis products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.CTCsSaliva