Residual Solvents per USP 467 Using Zebron ZB-624PLUS and ZB-WAXPLUS GC Columns

23 Sept 2018

Residual solvents in pharmaceutical products are defined as organic volatile chemicals that are used or produced in the manufacture of a drug substance, excipients, or preparation of a drug product. In this application note, learn how companies determine which solvents to use in production and subsequently develop testing procedures that are fit for purpose.

Zebron ZB-624plus

Phenomenex Inc

Zebron ZB-624PLUS is the optimal choice for the analysis of volatile compounds for Environmental, Pharmaceutical, Food, Cannabis, and Specialty Chemicals. The superior "Plus" deactivation process enhances peak shape, improves signal-to-noise levels and increases sensitivity for qualitative and quantitative analysis of active compounds. Upgrade your existing 624 phase to Zebron ZB-624PLUS GC columns and get all the analytical benefits of proven inertness. •    Enhanced Peak Shape with Superior Deactivation •    Increased Sensitivity for High Boiling Solvents •    Extremely Low Bleed for GC-MS •    High Temperature Stability (300/320 °C)  

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Zebron™ ZB-WAXplus GC Columns

Phenomenex Inc

100% Aqueous Stability for Polar Compounds100% aqueous stable, excellent for aqueous samples; bonded and solvent rinseableExtremely inert for acidic compoundsEnhanced selectivity for low boiling solvents; high retention of alcohols and chlorinated solventsIncreased efficiency at 20 °CZB-WAXplus provides optimal selectivity for many aqueous soluble compounds such as those found in alcoholic beverages or glycol samples. The ZB-WAXplus bonding process results in exceptional stability to repeated injections of aqueous matrices like whiskey. Multiple or routine water injections will not alter the efficiency or polarity of the phase over time.Recommended UseAlcohols, Aldehydes, Aromatics, Essential Oils, Flavors & Fragrances, Free Fatty Acids, Glycols, OVIs, Pharmaceuticals, Solvents / Residual Solvents, Styrene, Xylene IsomersEnhanced Aqueous Stability

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Residual Solvents per USP 467 Using Zebron ZB-624PLUS and ZB-WAXPLUS GC Columns