Rapid peptide mapping and monitoring of post translational modifications using high resolution ion mobility mass spectrometry
17 Jun 2021In this application note, explore how MOBILion’s HRIM-MS platform can be used as a high throughput alternative to long LC-MS gradients by providing a rapid peptide mapping protocol.
Incorporating HRIM into an LC-MS workflow provided >96.5% sequence coverage in just 20 minutes total analysis time and included critical structural information that would have been missed using conventional LC-MS techniques alone.
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MOBILion SystemsMOBILion Systems is disrupting the separations game, enhancing the way we characterize biotherapeutics and identify biomarkers. Leveraging a 13-meter ion mobility path length to provide deeper level characterization without compromising time, our best-in-class SLIM-based High-Resolution Ion Mobility Mass Spectrometry (HRIM-MS) platforms separate and identify molecules that current platforms fail to detect with faster analysis and simpler workflows.