ResourceSpectroscopy
Multi-method drug analysis in human plasma using a fault-tolerant high-throughput LC-MS/MS system
8 Oct 2026This scientific poster presents a high-throughput multiplex LC-MS/MS workflow for the simultaneous analysis of 26 drugs in human plasma using the Nexera QX and LCMS-8060RX platforms. Discover how four independent LC flow paths, integrated online SPE and parallel analytical methods help reduce carryover, minimize downtime, and improve laboratory productivity. Explore how the system achieved excellent linearity, robust quantitative accuracy, and approximately 60% higher throughput compared with conventional LC-MS/MS workflows, supporting efficient high-volume processing in forensic and clinical research laboratories.
Resource details:
Resource type: Scientific poster
Page count: 1
Read time: 5 mins
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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer.
LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.