More like life: Microporous membrane-based culture systems

3 May 2020

The value of cell culture experiments lies in how well they represent the native microenvironments of in vivo systems. In this application note, Millipore Sigma explores the advantages of using microporous membranes, compared to 2D plastic surfaces, to provide more in vivo-like cell growth environments for cell culture experiments.

Millicell® Cell Culture Inserts

Merck

With Millicell inserts, attachment or suspension cells can access media from both their apical and basolateral sides. Cell growth, structure, and function more closely mimic what occurs in vivo. In addition, Millicell inserts make it possible to study both sides of the cell monolayer. Millicell inserts are available for 24-, 12-, or 6-well plates.

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Millicell® 24 & 96-well Cell Culture Insert Plates

Merck

Millicell® cell culture insert plates are a patented device designed to support cell growth and differentiation of endothelial and epithelial cell lines, including CaCo-2. The Millicell® device is available with a 0.4 µm PCF and a variety of PET membrane pore sizes. The plate is designed for maximum user convenience and incorporates features such as apical assist for easier pipetting and basolateral access.

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