Miniature VHS Solenoid Valves Play Significant Role in the Viability of 3D Bio-Printing of Human Cells

Miniature VHS Solenoid Valves Play Significant Role in the Viability of 3D Bio-Printing of Human Cells

10 Feb 2016

The rapid development of viable inkjet technology for highly specialized applications, such as printing human cells, continues to generate significant interest. If successful, the realization of this technology for specialized biological applications, generally known as ‘biofabrication’, has the potential to replace the long established (and often controversial) process of using animals for testing new drugs. However, there are many challenges to overcome to enable the successful production of a valve-based cell printer for the formation of human embryonic stem cell spheroid aggregates. This application note demonstrates the use of VHS solenoid valves in the 3D bio printing of human cells.

Solenoid Control Valves

Lee Products Ltd.

2 and 3-way solenoid valves used to control the flow of liquids and gases. With these kinds of valves, the fluid is in contact with the valve's metal plunger.   LHD SERIES SOLENOID VALVES Lee's High Density Interface (LHD Series) Solenoid Valves are designed for applications where space is limited. Featuring small size and light weight without sacrificing performance and reliability, the valves are available in three different styles: plug-in, face mount, and ported. Extended performance versions (Quiet Operation, Semi-Inert and Lo-Lohm) are also available. These valves are generally used in medical and scientific instrumentation or control applications such as oxygen delivery systems, gas analysis equipment, patient monitors, air calibration devices, ventilators/respirators, gas chromatography and other flow switching devices. Each valve is 100% functionally tested for switching voltage, flow capacity and leakage. The rugged materials used help ensure consistent long-term performance. The valves will typically operate up to 250 million cycles on air, depending on the seal material and application parameters.   LHL SERIES SOLENOID VALVES Lee's LHL Series magnetic latching solenoid valves are designed for applications where space is limited. Featuring small size and light weight without sacrificing performance and reliability, the valves are available in three different styles: plug-in, face mount, and ported. The LHL Series latching valves are optimized for applications that demand ultra-low power (5.5 mJ per switch) and low heat making the valves ideal for portable, battery powered devices. The valves are also used in medical and scientific instrumentation or control applications such as oxygen delivery systems, gas analysis equipment, patient monitors, air calibration devices, ventilators/respirators, gas chromatography and other flow switching devices. Each valve is 100% functionally tested for switching voltage, flow capacity and leakage. The rugged materials used help ensure consistent long-term performance. The valves will typically operate up to 250 million cycles on air, depending on the seal material and application parameters.   LFA SERIES SOLENOID VALVES The Lee Interface Fluidic (LFA Series) Solenoid Valves offer small size and light weight, without sacrificing performance. Designed for applications where space is limited, these valves are generally used for medical and scientific applications flowing air or gas, such as blood chemistry instruments, ventilators/respirators, gas analysis equipment, blood pressure monitors and various other flow switching devices. LFA Series valves are available as a 2-way (normally closed) or 3-way soft tube ported design with two electrical connection options; printed circuit board mount or lead-wires.

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Solenoid Dispensing Valves

Lee Products Ltd.

2-way, high speed valves used to dispense small amounts of fluids.   VHS SERIES SOLENOID VALVES The Lee VHS valves are high speed, 2-way solenoid operated valves designed for applications requiring microliter and nanoliter dispense volumes. These applications include high throughput screening and drug discovery. The VHS valves feature: High speed operation: up to 1200 Hz Long life: 250 million cycles minimum Fast response: some models as fast as 0.25 ms Operating pressures up to 120 psi Wide range of seal materials   INK SERIES SOLENOID VALVES The Lee Company is the world leader in providing ink jet valves for drop on demand, large character printing. Featuring high speed, repeatability and long life, the INK Series valves are ideal for a replacement to existing printers or in new drop on demand and dispensing applications. Two mounting styles: Axial Pin and PC Board 275 Hz and 600 Hz models Low power consumption Long life, 250 million cycles minimum

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Solenoid Isolation Valves

Lee Products Ltd.

2 and 3-way valves that separate the working fluid (or gas) from the metal components of the valve. These are typically used with more aggressive liquids.   LFV SERIES SOLENOID VALVES The LFV Series is a family of 2-way isolation valves, featuring bi-directional flow and a contoured flow path which allows complete flushing. This contoured flow path also minimizes damage to "delicate" fluids. The small internal volume reduces the amount of fluid needed to fill the system (transport volume) further reducing sample and reagent requirements. LFV valves are optimized for applications in analytical instruments, biotechnology and IVD devices. Standard and Low Pressure Models Available 30 ms Response Time Operating Life of 10 Million Cycles Minimum Standard Operating Pressures up to 30 psid (Higher Pressures Available as Custom Designs) Low Power Consumption 12 and 24 vdc Models Low Internal Volume Zero Dead Volume Multiple Porting Options Manifold Mountable   LFR SERIES SOLENOID VALVES he LFR Series Micro Inert Valves (MIV) are 3-way inert solenoid valves designed for applications demanding high flow and small size. The different mounting combinations and porting options allow the designer the highest degree of freedom available. As Low as 700 Lohms Pressure Range: 28 in.  Hg Vac - 30 psig 30 ms Response Time 10 Million Cycles Minimum Power Consumption: 1.6 Watts 12 and 24 Volt Models Available with EPDM, FKM, or FFKM Diaphragm PEEK Porthead on all Models Manifold Mount, Barbed, and  1/4-28 Flat Bottom Boss Available   LFN SERIES SOLENOID VALVES The LFN Series Solenoid Valves are 2-way normally closed, diaphragm valves, designed to provide consistent reliable switching in the smallest footprint possible. The small footprint allows a high valve packing density on manifolds. Combining this with the valves' low internal volume greatly reduces the overall system fluid volume and manifold size. The isolation diaphragm on an inert housing makes these valves suitable for the control of critical and aggressive fluids. Small size: 0.3" center to center mounting Low internal volume: 13 microliters Fast response time: 20 ms (faster with a spike and hold circuit) Operating pressure: 30 psig Low Power: 900 mW   LFY SERIES SOLENOID VALVES The LFY Series are chemically inert solenoid valves which provide precise dispensing and control of aggressive and sensitive fluids. The LFY Series valves feature a unique internal configuration which minimizes damage to sensitive materials. Zero Dead Volume Standard (3,200 Lohm) and High Flow (1,000 Lohm) Models 2-way and 3-way models available Operating Pressures up to 30 psig Standard 12 and 24 vdc models available Low Internal Volume (as low as 18 microliters) Several mounting options for tube connections and manifold applications FKM and FFKM elastomers available 5 Million Cycles (minimum) service life

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Miniature VHS Solenoid Valves Play Significant Role in the Viability of 3D Bio-Printing of Human Cells