Measuring Small Quantities of Dry Powder Using the Aero S and Mastersizer 3000

The routine measurement of particle size plays an important role in pharmaceutical and other industries, where it is often a critical-to-quality attribute for the product. In this application note, aliquots as small as 5mg of fine grade, pharmaceutical lactose were measured to show that the measurement reproducibility is well within the ISO laser diffraction standard guidelines on repeatability. This fine grade of lactose is an established model material for active pharmaceutical ingredients.