ResourceLife Sciences
Live cell fluorescence-based phagocytosis assay using CELENA X High Content Imaging System
28 May 2026This application note demonstrates how the CELENA® X High Content Imaging System can be used to monitor and quantify phagocytosis in live cells using fluorescence-based assays. By tracking the uptake of pH-sensitive fluorescent E. coli particles over time, the workflow enables real-time visualization and measurement of phagocytic activity.
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CELENA® X High Content Imaging System
Logos BiosystemsThe CELENA ® X High Content Imaging System is an integrated imaging system designed for rapid, high content image acquisition and analysis.
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Cell ImagingCell imaging can be achieved using a number of techniques including confocal microscopy, transmission electron microscopy, atomic force microscopy, and light sheet microscopy.ImmunologyImmunology is the branch of medical science that covers the study of all aspects of the immune system of multicellular organisms.High Throughput ScreeningFluorescence MicroscopyFluorescence microscopy has become an essential tool in biology, as well as in materials science. The application of many fluorochromes has made it possible to identify cells and sub-microscopic cellular components with a high degree of specificity. Using multiple fluorescence labels, different probes can simultaneously identify several target molecules.Live Cell ImagingLive cell imaging is the study of living cells using microscopes and high-content imaging systems. This technique provides in-depth insight into fast and complex biological processes, by allowing dynamic imaging of living cells instead of acquiring an individual image at a single point in time.High Content ImagingHigh content imaging is a method combining two or more fluorescent microscopy experiments to identify substances that alter a cell’s phenotype in a desired manner. The process is adapted to multi-well plates and both the image acquisition and analysis are automated.Image AnalysisImage analysis involves the extraction of meaningful information from images, often using software to quantify and interpret visual data. It is widely used in cell biology, material science, and diagnostics. Increasingly, AI is being used to streamline image analysis. Explore image analysis tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Cell BiologyCell biology studies the structure, function, and behavior of cells. Understanding cellular processes is essential for research in areas such as cancer biology, stem cell research, and neurobiology. Techniques like flow cytometry, microscopy, and cell culture enable researchers to explore cellular mechanisms in detail. Browse our peer-reviewed product directory to find the best cell biology tools and equipment, compare products, check customer reviews, and get pricing directly from manufacturers.