ResourceSpectroscopy

Isobaric metabolites in urine analyzed with LCMS

22 Mar 2022

This application note demonstrates the ability to separate a wide variety of polar metabolites using mass spectrometry for detection. When monitoring the EIC at 133 m/z, seven peaks were positively detected in a urine sample by comparison with standards or by using accurate mass.

Cogent Diamond Hydride™ HPLC Columns

MicroSolv Technology Corp.

Cogent Diamond Hydride HPLC Columns are manufactured with TYPE-C™ silica (silica hydride) and a very small amount of carbon on the surface that adjusts the column hydrophobicity to an important level. This makes these columns have unique separation capabilities for scientists working in LCMS, metabolomics, bioanalytical, amino acids, organic acids, carbohydrates, and very polar small molecules.

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Isobaric metabolites in urine analyzed with LCMS