Honey authenticity testing using LC‑MS MS with streamlined sample preparation

6 May 2026

Explore a fast and reliable method for detecting 3‑methoxytyramine (3‑MT) in honey using the QSight® 500 LC‑MS/MS system from PerkinElmer. The approach uses a simplified Blend‑and‑Inject workflow that eliminates the need for solid‑phase extraction and isotopically labeled standards while maintaining high sensitivity and quantitative reliability. By addressing matrix challenges associated with high sugar content, the method supports efficient, high‑throughput authenticity testing and enables laboratories to detect beet‑sugar adulteration with reduced preparation time, lower costs, and improved operational efficiency.

QSight® 500 LC/MS/MS System

PerkinElmer

Designed to tackle the challenges faced by environmental testing labs analyzing PFAS and other emerging contaminants, the QSight® 500 LC/MS/MS System provides a robust solution for handling complex matrices. By minimizing sample preparation and enabling direct injection, this advanced system simplifies workflows, reducing the time and effort needed to achieve accurate results.

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LC-MS / MSFood AuthenticationFood authentication ensures that food products are accurately labeled and free from adulteration or misrepresentation. This is important for consumer safety, quality control, and regulatory compliance. Explore food authentication tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Quality ControlQuality control is needed in all production processes. Quality control is a monitoring procedure or set of procedures that are put in place to ensure that a manufactured product adheres to a defined set of quality criteria.
Honey authenticity testing with LC-MS/MS for 3-MT - SelectScience resources