EarlyTox Cardiotoxicity Kit Provides Biologically Relevant Cardiotoxicty Data Earlier in the Drug Discovery Process

15 Oct 2013

Assessing cardiotoxicity is important during early stages of drug discovery to eliminate potentially toxic compounds from further development. This application note describes a cardiotoxicity kit that provides a robust, high throughput method, using a novel calcium sensitive dye and a proprietary masking technology, to measure the impact of pharmacological compounds on stem cell-derived cardiomyocytes.

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Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.CytotoxicityCytotoxicity assays measure the toxic effects of substances on cells, often used in drug testing and environmental studies. These tests are crucial in determining the safety of chemicals and pharmaceutical compounds. Explore cytotoxicity testing tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Cardiotoxicity