Direct injection of drinking water for the analysis of 54 PFAS compounds by LC-MS/MS

16 Aug 2024

Per- and polyfluoroalkyl substances (PFAS) are a large, diverse group of synthetic compounds containing chains of linked carbon and fluorine atoms, and environmental exposure to PFAS has been linked to a variety of health issues in humans. To evaluate the health risk, an expanding list of governmental regulatory agencies have established validated methods stating the quantitative levels for individual or collective PFAS. Thermo Fisher Scientific aims to demonstrate the quantitative measurement of 54 PFAS compounds in water samples by direct injection with precision and accuracy that meets current European regulatory reporting requirements.

Thermo Scientific™ Vanquish™ Flex Binary UHPLC System

Thermo Fisher Scientific

The Thermo Scientific™ Vanquish™ Flex Binary UHPLC system is biocompatible with a state-of-the-art binary high-pressure pump and state-of-the-art binary solvent blending. This ultra high performance liquid chromatography system shares all Vanquish values, such as a design focused on uptime, robustness and reliability.

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LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.RegulatoryPharmaceutical regulations impact on all areas of drug development, manufacture and control and supply. Services are provided from the early stages of drug development and clinical trials through to dossier submission, approval and marketing. Regulatory also includes submission of analytical studies from the pharmaceutical product and safety. PFASLiquid Injection
Direct injection of drinking water for the analysis of 54 PFAS compounds by LC-MS/MS aligned with current and evolving global regulations