ResourceFood and Beverage
Determination of 6PPD-quinone & alternative PPD-quinones in fish tissue using QuEChERS with Serial Push-Thru Cartridge Cleanup
13 Jun 20256PPD-quinone (6PPD-Q) is an ozonation by-product of the tire antioxidant 6PPD, which emerging research shows poses a significant threat to aquatic ecosystems. As the concern over this class of contaminants grows, developing methods to extract and analyze various matrices is of the utmost importance.
Find out more about a QuEChERS extraction of a subset of PPD-Qs in salmon, combined with push-thru cartridge clean-up using UCT’s Quick QuEChERS®, C18, and LipiFiltr® in series to achieve the best level of sensitivity in the fatty matrix. Discover how by using UCT’s SelectraCore® C18 HPLC Column, an optimized analysis method was developed on LC-MS/MS.
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QuEChERSThe QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) method is a streamlined approach that is used to extract multi-residue target compounds from food samples. It is most commonly used by analytical chemists studying pesticide residues in food.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer.
ToxicityToxicity is defined as the degree to which a substance can harm humans or animals. It is essential to study the toxicity of pharmaceutical products during the development process so that optimum dosage can be established for the administration of the drug.Fish Tissue