Detection of Vaginitis Causing Pathogens

16 May 2018

Vaginitis results in >13 million physician office visits per year, and costs over $1 billion to the US healthcare system annually. However, up to 72% of women with vaginitis may remain undiagnosed or misdiagnosed. In this white paper, Luminex presents a summary of the condition and potential ways to effectively diagnose it in patients.

Related products

Request Quote for All Products

MicroPlex® Multiplexing Microspheres
Luminex
xMAP® Technology uses color-coded microspheres to detect multiple protein or oligonucleotide analytes from a single aliquot of sample in a single reaction well, enabling you to generate more data while saving sample, time, and reagents. Depending on your targets and the application, there are five different microsphere types to select from to produce the best experimental results. MicroPlex® are carboxylated polystyrene microspheres that have been dyed into 100 spectrally distinct sets or “regions”, allowing them to be individually identified by an xMAP instrument. In the multiplex assay environment the microspheres act as both the surface for the solution phase assay and the spectral identifier that the instrument detects. The open architecture of xMAP Technology enables users to build custom multiplex assays or select from a broad menu commercially available kits. MicroPlex microspheres are: Compatible with both protein and nucleic acid applications Available regions: 100 Available concentration: 12.5 (millions/mL) Available in multiple vial sizes: 1 mL, 4 mL, 16 mL Compatible xMAP instruments: FLEXMAP 3D®, Luminex® 100/200™ Additional xMAP microspheres: MagPlex®, MagPlex-TAG™, LumAvidin®, SeroMAP™
(0)
MagPlex-Avidin® Multiplexing Microspheres
Luminex
xMAP® Technology uses color-coded microspheres to detect multiple analytes from a single aliquot of sample in a single reaction well, enabling you to generate more data while saving sample, time, and reagents. Depending on your targets and the application, there are five different microsphere types to select from to produce the best experimental results. MagPlex-Avidin® are avidin-coupled magnetic polystyrene microspheres that have been dyed into 100 spectrally distinct sets or “regions”, allowing them to be individually identified by an xMAP instrument. In the multiplex assay environment the microspheres act as both the surface for the solution phase assay when reacted with a biotinylated ligand and the spectral identifier that the instrument detects. The open architecture of xMAP Technology enables users to build custom multiplex assays or select from a broad menu of commercially available kits. Each MagPlex-Avidin microsphere has deglycosylated avidin covalently coupled to its surface. Theto the surface of the addressable microsphere. For a complete protocol, visit the Luminex website. MagPlex-Avidin are ideal for coupling small molecules, like biotinylatese beads enable the user to quickly and easily design custom bead arrays, simply by reacting biotinylated target-specific ligand(s) with the MagPlex-Avidin microsphere; permanently linking the capture molecule(s) d peptides and offer: Avidin protein coated surface Near-covalent biotin-binding chemistry Available regions: 30 off the shelf (OTS), 70 additional regions built to order (BTO) Available concentration: 2.5 (millions/mL) Available vial sizes: 1 mL Compatible xMAP instruments: FLEXMAP 3D®(30 OTS and 70 BTO regions), Luminex® 100/200™ (30 OTS and 50 BTO regions), MAGPIX® (30 OTS and 20 BTO regions) Additional xMAP microspheres: MagPlex®, MagPlex-TAG™, MicroPlex®, SeroMAP™
(0)
Luminex® 200™Multiplexing Instrument
Luminex
The Luminex® 200™ detects up to 100 protein or nucleic acid analytes from a single aliquot of sample in a single reaction well, enabling you to generate more data while saving sample, time, and reagents. With more than 11,000 units sold globally to date, the Luminex 100/200 is the established standard in multiplexing instrumentation. The xMAP® multiplexing platform is composed of an instrument and associated reagents: The Luminex 200 instrument is based on the principles of flow cytometry, which integrates key xMAP detection components such as lasers, optics, fluidics, and high-speed digital signal processors. xMAP microspheres are a family of fluorescently dyed carboxylated polystyrene microspheres that act as both the surface for the solution phase assay and the spectral identifier that the instrument detects. The open architecture of xMAP Technology enables users to build custom multiplex assays or select from a broad menu commercially available kits. Instrument Details: Multiplex Capacity: Up to 100 non-magnetic; 80 magnetic Microtiter Plate: 96 well Throughput: ~40 min/96-well plate (up to 12,800 tests per hour) Dynamic Range: 3.5 logs Sensitivity: Detects a minimum of 1,000 fluorochromes of phycoerythrin (PE) per xMAP microsphere Optics: Lasers/APDs/PMTs Hardware: Flow Cytometry based Software: xPONENT® Software supports protocol-based data acquisition with robust data regression analysis Dimensions: All components combined (Analyzer, XY Platform and Sheath Delivery System) 26.5" W x 23.5" D x 12.5" H (67.3 cm W x 59.7 cm D x 31.8 cm H) Weight: All components combined (Analyzer, XY Platform and Sheath Delivery System) 113 lbs (49 kg) xMAP Reagent Compatibility: Magnetic and nonmagnetic microspheres
(10)
FLEXMAP 3D® Multiplexing Instrument
Luminex
The FLEXMAP 3D® detects up to 500 protein or nucleic acid analytes from a single aliquot of sample in a single reaction well, enabling you to generate more data while saving sample, time, and reagents. Fast read time, compatibility with both 96- and 384-well plates, and ease of integration with front-end automation systems make the FLEXMAP 3D the platform of choice for high-throughput bioassay applications. The xMAP® multiplexing platform is composed of an instrument and associated reagents: The FLEXMAP 3D® instrument is based on the principles of flow cytometry, which integrates key xMAP detection components such as lasers, optics, fluidics and high-speed digital signal processors. xMAP microspheres are a family of 500 fluorescently dyed carboxylated polystyrene microspheres that act as both the surface for the solution phase assay and the spectral identifier that the instrument detects. The open architecture of xMAP Technology enables users to build custom multiplex assays or select from a broad menu commercially available kits. Instrument Details: Multiplex Capacity: 500 Microtiter Plate: 96 well and 384 well Throughput: ~ 20 min/96-well plate (up to 144,000 tests/hour); ~ 75 mins/384-well plate (up to 153,600 tests/hour) Dynamic Range: 4.5 logs Sensitivity: Detects a minimum of 500 fluorochromes of phycoerythrin (PE) per xMAP microsphere Optics: Lasers/APDs/PMTs Hardware: Flow Cytometry based with dual sample fluidics paths and rapid sampling rate Software: xPONENT® Software offers interfacing options for front-end automation platforms and Laboratory Information Systems (LIS) Dimensions: 23” W x 25.7” D x 18” H (58.4 cm W x 65.3 cm D x 45.7 cm H) Weight: Up to 91 kg (200 lbs), including the instrument, monitor arm, monitor, and accessories, such as the keyboard, mouse and barcode scanner xMAP Reagent Compatibility: Magnetic and nonmagnetic microspheres
(3)