Comparison of sbeadex®Technology in Forensic PCR Clean Up
30 Apr 2013New approaches in forensic DNA typing technology mostly deal with the analysis of degraded and low copy number DNA with improvements being achieved by modifying PCR processes e.g. increase in the number of PCR cycles, reduction in reaction volume or the use of mini-STRs. In this application note low level DNA samples (artificial and routine casework) were amplified and subjected to two different PCR purification methods and the results compared.
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sbeadex Nucleic Acid Extraction Kits
LGC Biosearch TechnologiesOur proprietary sbeadex magnetic microparticles are designed to deliver high yields of high quality DNA, and have long enabled high throughput automated processing. sbeadex™ magnetic microparticles offer two key features which enable the extraction and purification of high quality DNA preparations: A novel two step binding mechanism via a patented adapter enables binding of nucleic acids more specifically. Final washes with pure water to deliver nucleic acids in high yield, purity and quality. Features: Development of customised protocols to your requirements Tailor-made extractions like modified lysis or eluation steps according to user requirements Extraction speed optimisation - quicker results Highly flexible batch sizes Technical advantages: Final washes with pure water to deliver nucleic acids in high yield, purity and quality No potential PCR inhibitors in wash buffers - e.g. organic solvents, salts, polyethyleneglycol Applicable for most popular robotic platforms (f.e. Hamilton, TECAN or KingFisher) Available sbeadex kits: sbeadex plant kit sbeadex blood kit sbeadex plasmid kit sbeadex forensic kit sbeadex tissue kit sbeadex livestock kit sbeadex pathogen kit The sbeadex technologies are suitable for high throughput automation and we have substantial experience developing sbeadex kits and protocols for use with a wide range of automation systems.