Cell therapy handbook

This handbook provides a comprehensive overview of cell therapy development and manufacturing, with a focus on CAR T cell therapies and emerging cell-based approaches. It covers key workflow stages including cell isolation, engineering, expansion, and cryopreservation, alongside regulatory considerations and supply chain challenges.

The resource also explores advances in gene editing technologies, automation, and allogeneic therapies, highlighting strategies to improve scalability, consistency, and patient access. Additionally, it discusses challenges such as manufacturing complexity, cost, and safety, as well as the growing role of alternative cell types and next-generation therapeutic approaches.