Bioluminescence Resonance Energy Transfer (BRET)-Based Studies of Receptor Dynamics in Living Cells with Berthold’s Mithras

Energy Transfer-based approaches represent the last major technical improvement in the field of membrane receptor biology. In application note 3 examples of BRET-based studies were used to investigate receptor dimerization, to follow the dynamic association between receptors and regulatory proteins, and to monitor the conformational changes induced by receptor activation.