Automation of a HTRF® Universal Methyltransferase Assay

14 Jan 2015

The study of epigenetic mechanisms affecting a wide range of cellular process has seen dramatic growth over the past several years. This application demonstrates the automation of an assay to measure methyltransferase activity in a 384-well format suitable for HTS and characterization of inhibitors of methyltransferase/substrate or methyltransferase/cofactor interactions.

Agilent BioTek Gen5 Software for Detection

Agilent Technologies

Agilent BioTek Gen5 software for Agilent BioTek multimode and single-mode microplate readers is an integrated tool for endpoint, kinetic, spectral scanning, and well area scanning. It controls all the functions of the plate reader and has powerful data analysis capabilities for a broad range of applications. Gen5 microplate reader software is also used to integrate BioTek plate readers to BioTek BioStack and other automated systems.

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Automation of a HTRF® Universal Methyltransferase Assay