ResourceLife Sciences
Automated Cell Separation Method Enhances Leukemia Patient Care
4 Jun 2014One of the major complications to occur following allogeneic stem cell transplantation in patients with malignant disease is relapse of the original disease. The re-emergence of patient cells may cause mixed chimerism in the patient’s bone marrow and blood. Chimerism analysis is usually performed by analysing polymorphic DNA sequences, most commonly by polymerase chain reaction (PCR), to determine the origin of cells. In the past, cell separation was achieved manually, which was labour intensive and time consuming. Now, however, a new automated method for cell separation is available.
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HematologyIn Haematology / Hematology, complete blood cell counts (or full blood counts) are obtained using automated blood count analyzers to enumerate blood cell types. Hematology also encompasses haemostasis and coagulation, thrombophilia and hemophilia, plasma viscosity and ESR analysis, hemoglobinopathies, cell morphology and haematinic measurement.ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Leukemia