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ATCC® Genetic Alteration Cell Line Panels: Effective Tools for High Throughput Screening Using Corning® Epic® Technology

Corning Life Sciences

ATCC® Genetic Alteration Cell Line Panels: Effective Tools for High Throughput Screening Using Corning® Epic® Technology

20 Jul 2015

This poster demonstrates how combining Corning Epic technology and the ATCC EGFR Genetic Alternation Panel offers a high sensitivity, label-free platform for the analysis of EGFR biology. This method is suitable for high-throughput screening and is a convenient tool for screening ligands or other biologics that directly target or affect EGFR biology.

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Axygen® 10 µL Maxymum Recovery® Microvolume Pipet Tips, Non-Filtered, Clear, Long Length, Bulk Pack

Corning Life Sciences

Axygen® Universal Tips are designed to fit a wide variety of single and multi-channel pipettors, compatible with most popular brands of pipettors. These polypropylene tips are nonpyrogenic and RNase-/DNase-free. They are available in Maxymum Recovery, beveled, nonsterile, sterile, non-filtered, and other features for specialized applications. Flexible walls and a series of internal sealing rings ensure a secure fit with less force required to load and eject.These polypropylene tips are RNase-/DNase-free.NonpyrogenicMicrovolumeMaxymum Recovery technology for ultra-low retention and high yieldCompatible with Eppendorf® pipettorsEppendorf® is a registered trademark of Eppendorf SE.

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Axygen® 10 µL Microvolume Pipet Tips, Non-Filtered, Clear, Long Length, Bulk Pack

Corning Life Sciences

Axygen® Universal Tips are designed to fit a wide variety of single and multi-channel pipettors. These polypropylene tips are nonpyrogenic and RNase-/DNase-free. They are available in Maxymum Recovery, beveled, nonsterile, sterile, non-filtered, and other features for specialized applications. Flexible walls and a series of internal sealing rings ensure a secure fit with less force required to load and eject.These polypropylene tips are RNase-/DNase-free.NonpyrogenicMicrovolumeMaxymum Recovery technology for ultra-low retentionCompatible with Eppendorf® pipettorsEppendorf® is a registered trademark of Eppendorf SE.

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BiosensorsBiosensors are devices used to detect an analyte using biological molecules specific to the analyte coupled to a detector. Biosensor instruments may be photometric, typically using surface plasma resonance (SPR), electrochemical or QCM (quartz crystal microbalance) biosensors. Biosensors should be selective, portable, robust and sensitive and have a fast response time. Systems may be manual or automated and usually have associated software.Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.High-Content ScreeningHigh-content screening (HCS), also known as high-content analysis (HCA), is a high-throughput technique used in drug discovery to identify substances that alter the phenotype of cells. HCS uses fluorescent microscopic imaging and automated image analysis to investigate cellular events such as apoptosis, cell viability, GPCR activation, oxide production, neurite outgrowth, and cell signaling. Find the best fluorescent labeling reagents, cellular assays, and high-content imaging systems in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cancer ResearchAlthough cancer is often referred to as a single condition, it actually consists of more than 100 different diseases. Microscopy, mass spectrometry, high throughput sequencing and flow cytometry are some of the most common techniques employed in cancer research labs.High ThroughputHigh throughput experiments allow the simultaneous processing of several samples. This parallelization reduces the cost per experiment and increases reproducibility and output volume of data.Drug DiscoveryDrug discovery is the process of identifying potential new medications, involving stages such as target identification, compound screening, and preclinical development. It relies on cutting-edge technologies like high-throughput screening, artificial intelligence, and molecular modeling to accelerate the identification of drug candidates. Drug discovery plays a pivotal role in developing new therapies for diseases ranging from cancer to rare genetic disorders. Browse our peer-reviewed product directory to find the latest drug discovery technologies, compare options, check customer feedback, and get pricing directly from manufacturers.Label-Free AnalysisGenome SequencingGenome sequencing involves determining the complete DNA sequence of an organism's genome. It provides crucial information about genetic variations, mutations, and diseases. Advances in sequencing technologies, such as next-generation sequencing (NGS), have accelerated research in genomics, diagnostics, and personalized medicine. Explore genome sequencing tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.EGFR

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