ResourceSpectroscopy

Analysis of Polar Ionic Pesticides by Ion-Exchange Chromatography Tandem Mass Spectrometry

30 May 2018

Learn how the application of high resolution ion-exchange chromatography, coupled to a triple quadrupole mass spectrometer, can overcome the issues experienced with other chromatographic techniques when analyzing polar ionic pesticides in food samples.

Thermo Scientific™ Dionex™ ICS-6000 Capillary HPIC™ System

Thermo Fisher Scientific

Obtain high performance, convenience, and flexibility by using a top-of-the-line IC platform optimized for capillary flow rates. The Thermo Scientific™ Dionex™ ICS-6000 Capillary HPIC™ System enables you to scale down column size, injection volumes, and flow rates by a factor of 25 to 100. With a capillary configuration, your system is always ready and able to run samples 24/7 with minimal calibration and equilibration time. These systems combine the all the advantages of high pressure ion chromatography and capillary IC. They are available in three configurations to match your application requirements. Choose from three configurations:       Dionex ICS-6000 Single Channel Capillary RFIC System use this single channel capillary IC system to run one analysis at a time, 24/7. Dionex ICS-6000 Dual Channel Capillary RFIC System This dual capillary system can run two different analyses concurrently on a single sample, or analyze two samples in parallel. Alternately, run the same analysis on both channels to double throughput. Dionex ICS-6000 Carbohydrates Analysis Capillary IC System use this capillary IC system for analyzing carbohydrates with ion exchange chromatography and electrochemical detection. High pressure ion chromatography, high performance Fast, sensitive separations without sacrificing resolution—up to two times faster with Fast IC columns Outstanding resolution using columns with small-diameter particles, thanks to high-pressure capability Continuous operation at up to 5000 psi when configured as a Thermo Scientific™ Reagent-Free™ IC (RFIC™) system Optimized peak resolution with a choice of isocratic and electrolytic gradient separations on each channel Powerful and user-friendly operation using the Thermo Scientific™ Chromeleon™ Chromatography Data System (CDS) Wide variety of chemistries available in Thermo Scientific capillary and Fast IC columns Flexible, easy to configure, modular design Flexible, easy to configure, modular design Time-saving dual system option The capillary advantage   Always ready with 24/7 uptime and minimal calibration and equilibration time Up to 18 months of continuous operation on one Eluent Generation cartridge Small dead volumes for minimized peak dispersion Reduced eluent disposal costs—only 15mL/day if eluent used for continuous operation at 10μL/min Enhanced ease-of-use: Dionex IC Cube houses capillary consumable cartridges with simple, colorcoded connections Flexible support for capillary columns of 0.2–0.6mm I.D. Application flexibility Typical flow rate range: 5–20μL/min Column i.d.: 02–0.6mm Typical yearly eluent usage: 5.25L Seamless sample preparation capabilities Dionex autosamplers integrate seamlessly with all Dionex ICS-6000 HPIC systems, providing effortless automation and advanced sample preparation capabilities.

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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. PesticidesPesticides are used to protect crops from diseases, pests and unwanted plants. They are classed as persistent organic pollutants (POPs) and can be harmful to humans. The Environmental Protection Agency (EPA) currently regulates the use of pesticides in the USA. ChromatographyChromatography is a powerful technique used to separate and analyze components of mixtures based on their chemical properties. It is widely used in fields like biochemistry, pharmaceuticals, and environmental analysis. By exploiting differences in the interaction of substances with a stationary phase and a mobile phase, chromatography enables precise purification and quantification of compounds. Whether you're working with complex biological samples or industrial chemicals, chromatography is essential for obtaining high-quality results. Browse our peer-reviewed product directory to find the best chromatography systems, compare products, read customer reviews, and get pricing directly from manufacturers.Food TestingFood testing refers to a variety experiments including PCR, mass spectrometry, processing, QuEChERS, analyzing and Kjeldahl.Food ContaminationFood contamination refers to the presence of harmful substances or pathogens in food, posing risks to human health. Contaminants can be biological, chemical, or physical, and their detection is crucial for ensuring food safety. Advanced testing methods like PCR, chromatography, and spectroscopy are used to identify contaminants in food products. Browse our peer-reviewed product directory to find the best solutions for food contamination detection, compare products, check reviews, and get pricing directly from manufacturers.