A Method to Streamline and Miniaturize Nextera™ Library Preparation for Illumina Next-Gen Sequencing
31 May 2017The ongoing evolution of next-generation sequencing (NGS) technologies has reduced sequencing costs by orders of magnitude and significantly increased throughput. Library preparation costs form a large proportion of the total cost of NGS, but there is potential to reduce these costs via miniaturization. This application note investigates two possible approaches to increase cost saving in library preparation workflows, enabled with Labcyte’s Echo 525 Acoustic Liquid Handler.
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Echo® 525 Liquid Handler
Beckman Coulter Life SciencesThe Echo 525 platform, like the other Echo liquid handler models, is designed to use sound energy to transfer reagents. Unlike the other Echo models, the Echo 525 platform transfers at a larger volume increment (25 nL). This enables the more rapid transfer of aqueous reagents required in biochemical and genomics assays setup.