A Mass-Spectrometry-Based Metabolic Phenotyping Strategy to Investigate the Molecular Response to Ionizing Radiation

A Mass-Spectrometry-Based Metabolic Phenotyping Strategy to Investigate the Molecular Response to Ionizing Radiation

6 Jul 2015

This poster applies a multi-platform, mass-spectrometry-based metabolic phenotyping strategy to the investigation into the molecular response of mouse serum to acute, gamma-radiation exposure. It also describes a potential molecular biosignature of radiation exposure and therefore a potential therapeutic target.

SYNAPT G2-Si MS

Waters

Transform your lab's discovery capability with the SYNAPT G2-Si MS. Information. Informatics. Impact. SYNAPT enables extensive characterization of complex mixtures and molecules with uncompromising qualitative and quantitative performance, streamlined workflows and unparalleled platform versatility. With the SYNAPT G2-Si you get ultimate UPLC/MS/MS performance, powerful data independent & data dependant solutions, CID and ETD fragmentation capabilities, and a wide range of experimental options.

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Xevo TQ-S

Waters

Xevo TQ-S tandem quadrupole mass spectrometer - designed for the most demanding quantitative UPLC/MS/MS applications. The ultimate in tandem quadrupole performance allows you to achieve unrivalled sensitivity and robustness, available to everyone due to the accessibility of the Xevo platform. The Xevo TQ-S gives you class leading sensitivity and robustness, qualitative information when you need it most and accelerated method development for sensitive and robust methods. Reducing complexity, increasing ease of use, and ensuring the correct result every time.

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ACQUITY UPLC BEH Columns

Waters

In 2004, Waters revolutionized liquid chromatography with the introduction of the ACQUITY UPLC System. At the heart of the system was Waters second generation hybrid, the Ethylene Bridged Hybrid (BEH) particle. In 2005, BEH Technology preparative particle sizes (2.5, 3.5, 5 and 10 μm) with the introduction of XBridge between HPLC and UPLC Technology platforms. BEH Technology particles offer: Excellent peak shape and efficiency for basic analytes A rational array of chromatographic selectivity Improvements in chemical stability at mobile phase extremes, particularly at elevated pH

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A Mass-Spectrometry-Based Metabolic Phenotyping Strategy to Investigate the Molecular Response to Ionizing Radiation