3D analysis of patient-derived tumor organoids

In this application note, Olympus’ FLUOVIEW^® FV3000 confocal laser scanning microscope and NoviSight^™ 3D software were used to quantitatively analyze patient-derived organoids (PDOs), in order to evaluate their morphological features and antibody binding of molecular targeted drugs. The combination of the high-resolution images of the FV3000 microscope, with the high recognition accuracy of NoviSight software meant that more reliable results of drug distribution and morphology were obtained.