2 Ways to Attain Sharper Peak Shape and Higher Sensitivity in Gas Chromatography
10 Apr 2016In gas chromatography the Method Detection Limit, or MDL, is the minimum concentration of a substance that can be measured with 99% confidence that the analyte concentration is greater than zero. It can be difficult for GC analysts to find a method sensitive enough to meet the MDLs, this technical note from Phenomenex addresses that issue by discussing two methods which produce a sharper peak shape and have higher sensitivity.
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Phenomenex IncLow Bleed, Intermediate Polarity Selectivity for GC/MSIntermediate polarity column for high molecular weight analysisInert to minimize analyte adsorption, improve efficiency, and reproducibilityMore rugged (longer column life) than other polar phasesExcellent for trace analysis with bleed-sensitive detectors (MS, FID, ECD, NPD)Recommended UseAmines, Aroclors, Drugs, EPA Methods (508, 608, 8081, 8141, 8151), Pesticides, Pharmaceuticals, Semi-volatiles, Steroids
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