Solid-phase extraction (SPE) is used for clean-up, extraction and concentration of semi-volatile or non-volatile analytes from complex mixtures including blood, urine and food samples. Multiple formats are available for conducting SPE, including prepacked SPE cartridges, disks and microplates, as well as SPE sorbent powders for manual packing. SPE systems can be used to automate the process and extract multiple samples at once. Solid-phase microextraction (SPME) and supported liquid extraction (SLE) products are also available in the same formats. Find the best SPE, SLE and SPME equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
Our HybridSPE ® -PLus plates effectively remove phospholipids and proteins from biological matrices in a simple pass-through method for accurate and reproducible LC-MS analysis. Unlike other phospholipid removal SPE products on the market, the unique retention mechanism of HybridSPE ® allows for separation of even very hydrophobic analytes from phospholipid contaminants.
Prevent sample failures in bioanalytical workflows
For method development and flexibility in sample and solvent volumes
Supel™ Swift HLB is a polymeric stationary phase for solid phase extraction (SPE) prior to instrumental analysis. It has both hydrophilic and lipophilic functional groups for the extraction of a broad range of compounds from aqueous samples. It retains analytes having diff erent polarities and Log P values due to its hydrophilic and lipophilic balance (HLB) property.
Faster and easier than SPE and liquid-liquid extraction: just load, wait 5 minutes, then elute
Simple and Accurate Fractionation for EPH Testing with New Silver Functionalized Enviro-Clean Fusion®Ag+ This novel sorbent is designed to help overcome the challenges associated with traditional silica gel fractionation. Featuring silver ions anchored onto a solid support, this chemistry provides enhanced selectivity, capacity, and overall performance.
Supel™ BioSPME 96-Pin Devices were developed to greatly improve upon the speed and simplicity plasma protein binding studies and other free analyte analyses. Our technology offers a 3x faster workflow compared to rapid equilibrium dialysis based methods, is amenable to both automation and manual operation, and is a convenient universal 96-pin format compatible with standard 96-well consumables.
A synthetic, optimized SLE sorbent that improves reproducibility for your extractions when compared to traditional diatomaceous earth SLE sorbents.
Supel™ Swift HLB is a polymeric stationary phase for solid phase extraction (SPE) prior to instrumental analysis. It has both hydrophilic and lipophilic functional groups for the extraction of a broad range of compounds from aqueous samples. It retains analytes having diff erent polarities and Log P values due to its hydrophilic and lipophilic balance (HLB) property.
MultiVac™ Vacuum Manifolds have 3-port and 6-port options in stainless steel and aluminum. Compatible with all Rocker filter holders and mainstream disposable funnels from Sartorious, Pall, and Millipore.
UCT's Enviro-Clean® Polymeric WAX Cartridges w/Polyethylene frits have been successfully utilized for the extraction of 26 diverse per- and polyfluoroalkyl substances (PFASs) in drinking water in addition to the 14 covered in the US EPA Method 537.
MultiSEP™ solid phase extraction wells from Thermo Electron offer robust and reproducible sample preparation and pre-concentration on a routine basis.Wells are available in pre-assembled plate format or as individual wells to allow customisable plates to be assembled by the user.Sorbent packings include the ever-popular silica based bonded phases and also include novel and unique chemistries for specialised applications. Multi…
The HySphere™ cartridge range has been specially developed for the Symbiosis / Prospekt on-line SPE system. The sorbents are exclusively developed by Spark to ensure optimal efficiency and reproducability for a wide range of compounds. The most important feature is the size of the sorbent particles, which is (for most sorbents) < 10 µm as compared to 40 µm in traditional SPE tubes. The elution volume of the 8 µm cartridge is m…
bed wt. 25 mg, volume 10 mL , (LRC), pk of 50 Application A class selective MIP phase for the multi-residue extraction of beta-agonists in urine, tissues, and other biological fluids. SupelMIP - Beta-agonists was developed for the selective extaction of a broad range o beta-agonists such as brombuterol, clenbuterol, formoterol, isoxuprine, mapenterol, ractopamine, ritrodine, salbutamol, salmeterol, terbutaline, tulobuterol, zi…
Commonly used for the solid phase extraction of analytes from complex sample matrices. A variety of functional groups, such as octadecyl (C18) and octyl (C8) can be bonded to the silica surface to provide non polar interactions. Each of these sorbents exhibits unique properties of retention and selectivity for a particular analyte. The choice of which sorbent is best for a particular method will be influenced by the percent…
Waters offers PoraPak™ Rxn, a family of polymer-based chromatography products for superior cleanup of synthetic reactions. PoraPak Rxn products are available in two chemistries: PoraPak Rxn CX, a strong cation-exchange sorbent and PoraPak Rxn RP, a reversed-phase sorbent.PoraPak Rxn sorbents are based on copolymers that exhibit the following properties:Hard material that does not develop increasing back pressure with flowLitt…
Patent pending HybridSPE – Precipitation (HybridSPE-PPT) technology is a simple and generic sample prep platform designed for the gross level removal of endogenous protein and phospholipid interferences from biological plasma and serum prior to LC-MS or LC-MS/MS analysis. Biological plasma or serum is first subjected to protein precipitation via the addition and mixing of acidified acetonitrile. Precipitated proteins are then…
3M Bioanalytical's Empore ci8 47mm Disk - Commonly used for the solid phase extraction of analytes from complex sample matrices. A variety of functional groups, such as octadecyl (C18) and octyl (C8) can be bonded to the silica surface to provide non polar interactions. Each of these sorbents exhibits unique properties of retention and selectivity for a particular analyte. The choice of which sorbent is best for a particu…
SDB-XC is a poly(styrenedivinylbenzene) copolymer used as a reversed phase sorbent for solid phase extraction. SDB-XC is not bonded to silica but is a 100% copolymeric particle that is spherical, porous and cross-linked. It does not exhibit the secondary cationic (silanol) interactions and pH limitations common to bonded silica sorbents, so it offers more predictable and reproducible reversed phase interaction.
SDB-RPS is a poly(styrenedivinylbenzene) copolymer that has been modified with sulfonic acid groups to make it hydrophilic. SDB-RPS is not bonded to silica but is a 100% copolymeric particle that is spherical, porous and cross-linked. The sulfonation imparts unique selectivity for organic analytes that are polar in nature, such as drugs, drug metabolites, water-soluble pesticides and pesticide metabolites. SDB-RPS is also u…
Cation-SR is a poly(styrenedivinylbenzene) copolymer that has been modified with sulfonic acid. Note that Cation-SR is not bonded to silica but is a 100% copolymeric particle that is spherical, porous and cross-linked. The functional group imparts selectivity for cationic analytes, such as primary, secondary and tertiary amines.
3M Bioanalytical Anion-SR is a poly(styrenedivinylbenzene) copolymer that has been modified with quaternary ammonium groups. Note that the 3M Anion-SR is not bonded to silica but is a 100% copolymeric particle that is spherical, porous and cross-linked. The functional group imparts unique selectivity for anionic analytes, such as Endothall, Dalpon and haloacetic acids.
The Oil & Grease Disk was specifically designed for EPA Method 1664 (N-Hexane Extractable Materials (HEM) and Silica Gel Treated N-Hexane Extractable Material (SGT-HEM) by Extraction and Gravimetry). EPA Method 1664 Revision A was approved for use in the United States and published in the Federal Register on May 14, 1999. The Oil & Grease Disk incorporates C18 sorbent particles within a hydrophobic matrix. For EPA Method 166…
Empore™ Chelating Disks provide a way to selectively remove multivalent metal cations from solutions. This selectivity can be used to concentrate metals from a sample for analysis or to isolate and remove metal interferences from a complex organic or inorganic sample matrix. In the latter case, the purified filtrate is ready for use. The chelating disk has an affinity for multivalent (primarily 2+ and 3+) transition element…
