Combinatorial Chemistry Products & Reviews

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Combinatorial chemistry, also known as combichem, is a technique used in drug discovery to create libraries of structurally related compounds. A library is generated by synthesis with a chemical reactor system or by computer-based modeling of compound combinations. When undertaking combinatorial chemistry consider reagents, buffers, resins and standards.

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Biotage® PeptiPEC-96 High Throughput Kit

Biotage

Biotage® PeptiPEC-96 High Throughput Kits streamline peptide purification with the automated PurePep® Easy Clean (PEC™) catch-and-release strategy. Purify 96 peptides simultaneously while removing impurities efficiently for cleaner, higher-quality peptide libraries.

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Biotage® PeptiRen-96 Well-plate

Biotage

Biotage® PeptiRen-96 well plates streamline peptide library workflows by enabling simultaneous post-synthesis clean-up of 96 crude peptides. Featuring reversed-phase media optimized for peptide SPE, they provide an efficient, automatable solution for rapid enrichment and preliminary screening.

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synthWAVE microwave synthesis system

Milestone

The Milestone synthWAVE is designed for safe, reliable and reproducible scale-up of microwave enhanced chemical reactions. The synthWAVE is capable of higher temperature and pressure than any other microwave reactors. Milestone synthWAVE features the unmatched Single Reaction Chamber (SRC) patented technology that ensures scale, reaction screening, highest temperature and pressure. It is able to handle single or multiple react…

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flexiWAVE Microwave Synthesis System

Milestone

The new Milestone flexiWAVE overcomes the limitation of conventional microwave synthesis reactors, as it consists of a single microwave platform that, in combination with specific accessories, allows the chemists to perform classic glassware and high pressure synthesis, as well as solid-phase reactions.

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Phage Display AlVHHL-2 Alpaca Naïve Single Domain Antibody Library Screening Service

Creative Biolabs

The Phage Display AlVHHL-2 Alpaca Single Domain Antibody Library excels due to its vast library size and significant genetic variety produced from multiple alpacas. The combination of broad genetic diversity and single-domain antibodies delivers precise solutions for complex scientific challenges that standard antibody libraries find difficult to address.

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Custom Nucleic Acid Production Services

Creative Biolabs

Custom DNA/RNA oligonucleotide synthesis with broad modification choices (PS, 2′-OMe, 2′-F, LNA, GalNAc, dyes/biotin), multiple scales and purifications, and analytical QC. Includes design consultation and documentation to support research, translational studies, and conjugation-ready formats.

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Phage Display CaVHHL-S2 Camel Synthetic Single Domain Antibody Library Screening Service

Creative Biolabs

Creative Biolabs provides screening services for the CaVHHL-S2 Camel Synthetic Single Domain Antibody Library but does not sell the library directly. Our advanced M13 pIII fusion phage display technology combined with high-throughput screening platforms enables clients to rapidly identify ideal antibody candidates while resolving issues like extended screening durations and the detection of low-affinity antibodies.

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Phage Display HuVHHL-S1 Humanized Synthetic Single Domain Antibody Library Screening Service

Creative Biolabs

The Phage Display HuVHHL-S1 Humanized Synthetic Single Domain Antibody Library serves as a leading resource to expedite the discovery of high-quality antibodies with exceptional specificity. Our library makes efficient identification of optimized drug candidates possible through the use of advanced humanization and randomization technologies, together with a strong high-throughput screening platform.

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Circular RNAs (circRNAs) Services

Creative Biolabs

Comprehensive circRNA services including design, circularization (e.g., ribozyme/intron-mediated), purification, and analytics to deliver stable, translation-competent RNA with improved durability—supported by process development for research and translational programs.

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Custom Viral Vector Development Services

Creative Biolabs

End-to-end viral vector design and construction covering vector/serotype selection, expression-cassette optimization, cloning, packaging, purification, and QC. Supports AAV, lentivirus, adenovirus, HSV, vaccinia, and baculovirus with scalable production and documentation for in vitro/in vivo studies and IND-enabling work.

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GenScript Targeted LNP: Precision Delivery for Enhanced Therapeutics

GenScript

The Targeted LNP service offers custom-made lipid nanoparticle formulations designed for precise therapeutic payload delivery. Enhanced with optimized antibodies and ligands, these LNPs enable targeted delivery to specific cell types, including T cells, lungs, spleen, tumors, brain, liver, and macrophages. Achieve efficient, tissue-specific delivery with GenScript’s advanced LNP technology.

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