Combinatorial Chemistry Products & Reviews

Custom peptide service with more than 300 modification choices

GenScript’s Neoantigen Peptide Synthesis Service supports everything from functional screening of neoantigen candidates for TCR therapy to clinical stage vaccine immunogenicity testing.

The Milestone synthWAVE is designed for safe, reliable and reproducible scale-up of microwave enhanced chemical reactions. The synthWAVE is capable of higher temperature and pressure than any other microwave reactors. Milestone synthWAVE features the unmatched Single Reaction Chamber (SRC) patented technology that ensures scale, reaction screening, highest temperature and pressure. It is able to handle single or multiple react…

The new Milestone flexiWAVE overcomes the limitation of conventional microwave synthesis reactors, as it consists of a single microwave platform that, in combination with specific accessories, allows the chemists to perform classic glassware and high pressure synthesis, as well as solid-phase reactions.

Twist Multiplexed Gene Fragments are double stranded gene fragment sequences of up to 500 base pairs in length that are delivered as a pool instead of one fragment per well matrix.

As a leading provider of peptide synthesis services, Alfa Chemistry can supply high-quality beauty peptides to cosmetic companies looking to create innovative skincare products. Our beauty peptide product line focuses on specific skin concerns, and our experienced chemists use state-of-the-art facilities and quality control measures to ensure the safety and purity of our peptides.

More than ten years of synthesis experience working with both life sciences and specialty chemicals companies enable Alfa Chemistry to complete any challenging custom synthesis project from milligram to kilogram scale. We will safeguard your confidentiality, as our clients retain all intellectual property of their research.

Alfa Chemistry has been providing custom synthesis services for building blocks to customers worldwide. Our featured products include mainly pyridines, boric acids, miscellaneous and chiral molecules.

As a leading product R&D, production and sales integration company in peptide, Alfa Chemistry supplies high quality of hydrolyzed protein peptides, fish collagen peptide, marine fish oligopeptide, oyster peptide, sea cucumber Peptide, pea peptide, soy peptide and walnut peptide. And they can be used in food, beverage, liquid dairy products, medicine and health care products.

Alfa Chemistry provides synthetic peptides with a wide range of labels, scales, purities and delivery time options to meet your research needs. We ensures that each custom peptide is triple checked for quality via both mass spectrometry(MS) and high performance liquid chromatography (HPLC) analyses after each step during peptide purification and quality control (QC) procedures.

Versatile Dispense Connectors for Safe, Efficient Chemical Handling

The LlaVHHL-2 Llama Naïve Single Domain Antibody Library is a state-of-the-art resource for efficient, high-quality antibody screening. Designed to meet the diverse needs of researchers, this library provides access to a rich pool of sdAbs derived from llama naïve antibody genes.

Tailored formulation and conjugation for nucleic acids and biologics, covering LNPs and alternative carriers, ligand-directed strategies (e.g., GalNAc), and full characterization and process development to enhance stability, targeting, and potency with documentation for scale-up and regulatory needs.

The Phage Display AlVHHL-2 Alpaca Single Domain Antibody Library excels due to its vast library size and significant genetic variety produced from multiple alpacas. The combination of broad genetic diversity and single-domain antibodies delivers precise solutions for complex scientific challenges that standard antibody libraries find difficult to address.

Custom DNA/RNA oligonucleotide synthesis with broad modification choices (PS, 2′-OMe, 2′-F, LNA, GalNAc, dyes/biotin), multiple scales and purifications, and analytical QC. Includes design consultation and documentation to support research, translational studies, and conjugation-ready formats.

Creative Biolabs provides screening services for the CaVHHL-S2 Camel Synthetic Single Domain Antibody Library but does not sell the library directly. Our advanced M13 pIII fusion phage display technology combined with high-throughput screening platforms enables clients to rapidly identify ideal antibody candidates while resolving issues like extended screening durations and the detection of low-affinity antibodies.

Integrated ASO development from sequence design and chemistry selection to preclinical PK/PD, safety, delivery (e.g., GalNAc), and CMC—supporting gapmer and steric-blocker approaches to advance programs efficiently toward IND.

The Phage Display HuVHHL-S1 Humanized Synthetic Single Domain Antibody Library serves as a leading resource to expedite the discovery of high-quality antibodies with exceptional specificity. Our library makes efficient identification of optimized drug candidates possible through the use of advanced humanization and randomization technologies, together with a strong high-throughput screening platform.

Comprehensive circRNA services including design, circularization (e.g., ribozyme/intron-mediated), purification, and analytics to deliver stable, translation-competent RNA with improved durability—supported by process development for research and translational programs.

The HuScL-6 Human Single Chain Antibody Library is a state-of-the-art resource for efficient, high-quality antibody screening. Designed to meet the diverse needs of researchers, this library provides access to a rich pool of scFv antibodies derived from human naïve antibody genes.

End-to-end viral vector design and construction covering vector/serotype selection, expression-cassette optimization, cloning, packaging, purification, and QC. Supports AAV, lentivirus, adenovirus, HSV, vaccinia, and baculovirus with scalable production and documentation for in vitro/in vivo studies and IND-enabling work.

Vapourtec offers a range of world class peptide synthesizer systems offering fast flow solid phase peptide synthesis from 0.05 mmol to 30 mmol.

ISOAPI-D™: Built Specifically for the Next Generation of Deuterated Reagents in Pharmaceutical Development

Stable Isotope-labeled Gases and Packaging Options